SCHEMBL172479

SCHEMBL172479

C=CC(=O)Oc1ccc(-c2ccc(N(c3ccc(C)cc3)c3ccc(-c4ccc(OC(=O)C(=C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ THRB P10828 2/20 0.43
▸ ELANE P08246 1/20 0.42
▸ LMNA P02545 1/20 0.41
▸ KMT2A Q03164 3/20 0.39
▸ ATM Q13315 1/20 0.39
▸ ALDH1A1 P00352 2/20 0.36
▸ MAPT P10636 2/20 0.34
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ PDE6D O43924 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ TSHR P16473 1/20 0.32
▸ MAPK1 P28482 1/20 0.32
▸ HTT P42858 1/20 0.32
▸ TGM2 P21980 1/20 0.31
▸ GFER P55789 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11987033 1.00 THRB (0.43) THRBELANELMNAKMT2AATM
SCHEMBL11987039 1.00 THRB (0.43) THRBELANELMNAKMT2AATM
SCHEMBL12234101 1.00 THRB (0.43) THRBELANELMNAKMT2AATM
SCHEMBL12234088 0.96 THRB (0.46) THRBELANELMNAKMT2AATM
SCHEMBL12234108 0.95 ELANE (0.47) THRBELANELMNAKMT2AATM
SCHEMBL11987034 0.92 ELANE (0.48) ELANELMNAKMT2AATMALDH1A1
SCHEMBL13051075 0.92 ELANE (0.48) ELANELMNAKMT2AATMALDH1A1
SCHEMBL9915703 0.92 ELANE (0.48) ELANELMNAKMT2AATMALDH1A1
SCHEMBL2542979 0.92 ELANE (0.48) ELANELMNAKMT2AATMALDH1A1
SCHEMBL9915701 0.92 ELANE (0.48) ELANELMNAKMT2AATMALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8335456-B2 Image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2012-12-18 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
US-8247143-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2012-08-21 — — US disclosed
EP-1847881-B1 Image forming apparatus, image forming method, and process cartridge RICOH CO LTD (JP) 2012-03-07 — — EP disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-8043773-B2 surface layer having a good anti-abrasion property, good electric characteristics and a good cleaning property for a spherical toner; photosensitive layer on an electroconductive substrate; Particulates having a needle form are dispersed in the surface layer of the photosensitive layer RICOH COMPANY, LIMITED (JP) 2011-10-25 — — US disclosed
US-7985520-B2 Photoreceptor, image formation method, image forming apparatus and process cartridge RICOH COMPANY, LTD. (JP) 2011-07-26 — — US disclosed
US-20080318142-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, METHOD FOR PREPARING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, AND IMAGE FORMING METHOD AND APPARATUS AND PROCESS CARTRIDGE USING THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR RICOH COMPANY, LTD. (JP) 2008-12-25 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-7449272-B2 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2008-11-11 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080241716-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2008-10-02 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20080153021-A1 IMAGE BEARING MEMBER, IMAGE FORMING APPARATUS AND PROCESS CARTRIDGE RICOH COMPANY LIMITED (JP) 2008-06-26 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
US-20070297836-A1 IMAGE FORMING APPARATUS, IMAGE FORMING METHOD, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2007-12-27 — — US disclosed
EP-1847881-A2 Image forming apparatus, image forming method, and process cartridge Ricoh Company, Ltd. (JP) 2007-10-24 — — EP disclosed
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