SCHEMBL1724862

SCHEMBL1724862

OC1(c2ccccc2)CCC1

nearest known ligand 0.57

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
OPRL1 P41146 12/20 0.57
OPRM1 P35372 7/20 0.57
OPRK1 P41145 7/20 0.57
OPRD1 P41143 5/20 0.52
POLB P06746 1/20 0.50
AKR1C1 Q04828 1/20 0.46
SIGMAR1 Q99720 1/20 0.46
HSD11B1 P28845 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL29195223 0.97 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL1109741 0.95 OPRL1 (0.57) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL4556223 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL16469256 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL1041473 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL60129 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL29195226 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
Hydrogen Peroxide SCHEMBL14842577 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL1040024 0.92 OPRL1 (0.55) OPRL1OPRM1OPRK1OPRD1POLB
SCHEMBL9022765 0.90 OPRL1 (0.48) OPRL1OPRM1OPRK1OPRD1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117718081-A Tetravalent uranium photocatalyst and synthesis method thereof 南京大学 2024-03-19 CN claimed
CN-122071411-A Method for forming ester by oxidizing and breaking carbon-carbon bond by tertiary alcohol 中国科学院大连化学物理研究所 2026-05-22 CN disclosed
CN-118930426-A Method for preparing benzoic acid and derivatives thereof from tertiary alcohol 中国科学院大连化学物理研究所 2024-11-12 CN disclosed
CN-117718081-A Tetravalent uranium photocatalyst and synthesis method thereof 南京大学 2024-03-19 CN disclosed
CN-117603090-A Method for breaking and forming tetravalent uranium photocatalytic carbon-carbon bond 南京大学 2024-02-27 CN disclosed
CN-115894141-B Method for synthesizing acyl indene alkane derivative 贺州学院 2023-12-22 CN disclosed
CN-115894141-A Synthesis method of acylindene derivatives 贺州学院 2023-04-04 CN disclosed
CN-113651752-B Synthesis method of 2-aroylquinoline derivative 温州大学 2023-02-10 CN disclosed
CN-113636977-B Synthesis method of 2-aryl benzazepine and derivatives thereof 温州大学 2022-12-20 CN disclosed
CN-112110801-B Synthetic method of gamma-aryl substituted ketone compound 浙江工业大学 2022-07-19 CN disclosed
US-20070219265-A1 SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS ALLERGAN, INC. 2007-09-20 US disclosed
US-20070219265-A1 SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS ALLERGAN, INC. 2007-09-20 US disclosed
CN-1344270-A Functionalized heterocycles as chemokine receptor modulators THOUSAND YEARS MEDICAMENTS INC (US) 2002-04-10 CN disclosed
EP-1144415-A2 FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS WARNER-LAMBERT COMPANY (US) 2001-10-17 EP disclosed
EP-0682663-B1 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS UPJOHN CO (US) 2001-04-18 EP disclosed
WO-2000042045-A2 FUNCTIONALIZED HETEROCYCLES AS CHEMOKINE RECEPTOR MODULATORS WARNER-LAMBERT COMPANY (US) 2000-07-20 WO disclosed
US-5686486-A 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl b!pyran-2-ones useful to treat retroviral infections PHARMACIA & UPJOHN COMPANY (US) 1997-11-11 US disclosed
EP-0682663-A1 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS PHARMACIA & UPJOHN COMPANY (US) 1995-11-22 EP disclosed
WO-1994018188-A1 4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS THE UPJOHN COMPANY (US) 1994-08-18 WO disclosed
US-4256618-A DISCOLORATION INHIBITION DURING EARLY HEATING; SYNERGISTIC ARGUS CHEMICAL CORPORATION (US) 1981-03-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070219265-A1 SUBSTITUTED GAMMA LACTAMS AS THERAPEUTIC AGENTS GLA, GUSB, GANAB OPRL1 2323/4885OPRM1 1425/4885OPRK1 1110/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.