Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 8/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1724862 | 0.90 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| Ammonia Solution, Strong SCHEMBL29195223 | 0.88 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| SCHEMBL1109741 | 0.85 | OPRL1 (0.57) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| SCHEMBL34468465 | 0.85 | OPRL1 (0.50) | OPRL1OPRM1OPRK1OPRD1POLB | |
| SCHEMBL60129 | 0.83 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| SCHEMBL1040024 | 0.83 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| Hydrogen Peroxide SCHEMBL14842577 | 0.83 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| SCHEMBL29195226 | 0.83 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| SCHEMBL4556223 | 0.83 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 | |
| SCHEMBL16469256 | 0.83 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8259480-A | — | — | None | — | — | JP | disclosed |
| JP-H08259480-A | CYCLOALKANE-1,3-DIOL NEW HOST COMPOUND | ASAHI CHEM IND CO LTD | 1996-10-08 | — | — | JP | disclosed |