Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.52 |
| ▸ | SPOP | O43791 | 11/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17133107 | 0.88 | TDP1 (0.61) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL17432896 | 0.77 | TDP1 (0.52) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL14029032 | 0.75 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL14458878 | 0.75 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10385707 | 0.75 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL14389917 | 0.74 | TDP1 (0.62) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL5794628 | 0.73 | TDP1 (0.56) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL13806385 | 0.73 | TDP1 (0.65) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9999529 | 0.73 | TDP1 (0.72) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL17049621 | 0.72 | TDP1 (0.49) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150322087-A1 | CEPHALOSPORIN DERIVATIVES AND METHODS OF USE | UNIVERSITY OF KANSAS | 2015-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322087-A1 | CEPHALOSPORIN DERIVATIVES AND METHODS OF USE | CNDP2, CLSPN, PEPD | TDP1 2691/4885MAPT 3384/4885ABCC4 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.