Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.51 |
| ▸ | SPOP | O43791 | 12/20 | 0.49 |
| ▸ | APAF1 | O14727 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.48 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509704 | 0.89 | TDP1 (0.48) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9481759 | 0.74 | TDP1 (0.51) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL17249474 | 0.73 | TDP1 (0.56) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL10385707 | 0.73 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL14458878 | 0.73 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL14029032 | 0.73 | TDP1 (0.58) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL14389917 | 0.73 | TDP1 (0.62) | TDP1MAPTABCC4CNR1CTDSP1 | |
| SCHEMBL9999529 | 0.72 | TDP1 (0.72) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL5919457 | 0.72 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 | |
| Cefdinir SCHEMBL1559599 | 0.72 | TDP1 (1.00) | TDP1MAPTABCC4CNR1CTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006010978-A1 | CEFDINIR POLYMORPHIC FORMS, AND IMIDAZOLE SALT | WOCKHARDT LIMITED (IN) | 2006-02-02 | — | — | WO | disclosed |