⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5697037 | 0.77 | — | — | |
| SCHEMBL6052962 | 0.77 | — | — | |
| SCHEMBL28227175 | 0.75 | — | — | |
| SCHEMBL127300 | 0.73 | TSHR (0.38) | — | |
| SCHEMBL1343929 | 0.73 | — | — | |
| SCHEMBL16370025 | 0.73 | — | — | |
| SCHEMBL11042790 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL3341220 | 0.73 | — | — | |
| SCHEMBL6052827 | 0.73 | — | — | |
| SCHEMBL5697306 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119192219-A | Preparation method of cyano-terminated siloxane | 杭州师范大学 | 2024-12-27 | — | — | CN | claimed |
| CN-113912537-B | 2- (Quinoline-8-yl) carbonyl-cyclohexane-1, 3-dione compound and preparation method and application thereof | 重庆化工职业学院 | 2024-05-07 | — | — | CN | claimed |
| CN-113912537-A | 2- (quinoline-8-yl) carbonyl-cyclohexane-1, 3-diketone compound and preparation method and application thereof | 重庆化工职业学院 | 2022-01-11 | — | — | CN | claimed |
| CN-108178724-B | Process for the preparation of compounds | 四川大学 | 2020-09-11 | — | — | CN | claimed |
| US-7763746-B2 | minimizing decomposition of cyanohydrins in an exothermic reaction process involving hydrolysis reactions of acetone cyanohydrin; controlling the temperature; produce a monomer selected from methacrylic acid and methyl methacrylate | ROHM AND HAAS COMPANY (US) | 2010-07-27 | — | — | US | claimed |
| US-7582790-B2 | minimizing decomposition of cyanohydrins in an exothermic reaction process involving hydrolysis reactions of acetone cyanohydrin; controlling the temperature; produce a monomer selected from methacrylic acid and methyl methacrylate | ROHM AND HAAS COMPANY (US) | 2009-09-01 | — | — | US | claimed |
| US-20090082587-A1 | minimizing decomposition of cyanohydrins in an exothermic reaction process involving hydrolysis reactions of acetone cyanohydrin; controlling the temperature; produce a monomer selected from methacrylic acid and methyl methacrylate | SCHLADENHAUFFEN PAUL BENJAMIN | 2009-03-26 | — | — | US | claimed |
| EP-1234046-B1 | UDP-GLUCOSE:AGLYCON-GLUCOSYLTRANSFERASE | ADELAIDE RES & INNOVATION PTY (AU) | 2008-11-12 | — | — | EP | claimed |
| US-6743938-B1 | DIETHYLAMINE CATALYTIC REACTION OF HYDROCYANIC ACID AND METHYL ETHYL KETONE | ATOFINA (FR) | 2004-06-01 | — | — | US | claimed |
| CN-1415017-A | Uridine diphosphate glucuronosyl-glucosyltransferase | ADERAD RES INNOVATION GMBH (AU) | 2003-04-30 | — | — | CN | claimed |
| US-6207705-B1 | FOR KILLING INSECTS, TICKS, NEMATODES, THEIR EGGS AND LARVE; VOLATALITY, FUMICATION, NONTOXIC | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2001-03-27 | — | — | US | claimed |
| US-5834618-A | CHEMICAL INTERMEDIATE FOR PROTEASE INHIBITOR DRUG | KURARAY CO., LTD. (JP) | 1998-11-10 | — | — | US | claimed |
| EP-0412310-B2 | Process for producing Manganese dioxide catalyst for the hydration reaction of cyanohydrins | MITSUBISHI GAS CHEMICAL CO (JP) | 1996-10-09 | — | — | EP | claimed |
| US-5175366-A | Process for producing a denaturated manganese dioxide catalyst for the hydration reaction of cyanohydrins | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1992-12-29 | — | — | US | claimed |
| EP-0510689-A1 | Hydrocyanation of pentenenitriles using cyanohydrins | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-10-28 | — | — | EP | claimed |
| US-5107012-A | Using an additive to promote dissociation of the cyanohydrin, a nickel complex catalyst and catalyst promoter; slurrying | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-21 | — | — | US | claimed |
| US-5091555-A | Recirculating unreacted material | DEGUSSA AG (DE) | 1992-02-25 | — | — | US | claimed |
| EP-0412310-A1 | Process for producing Manganese dioxide catalyst for the hydration reaction of cyanohydrins | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1991-02-13 | — | — | EP | claimed |
| EP-0043490-B1 | PREPARATION OF ACYL CYANIDES | BAYER AG (DE) | 1983-09-28 | — | — | EP | claimed |
| US-4246189-A | FOR EASE OF MATERIALS HANDLING | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1981-01-20 | — | — | US | claimed |