⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL496792 | 0.82 | HDAC1 (0.31) | — | |
| SCHEMBL451027 | 0.62 | KDM4C (0.34) | — | |
| SCHEMBL630634 | 0.60 | HDAC6 (0.41) | — | |
| SCHEMBL366089 | 0.60 | HDAC1 (0.32) | — | |
| SCHEMBL14486331 | 0.60 | — | — | |
| SCHEMBL1522051 | 0.60 | IDO1 (0.52) | — | |
| SCHEMBL15563778 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL7988951 | 0.58 | HDAC6 (0.40) | — | |
| SCHEMBL1327552 | 0.58 | HDAC1 (0.30) | — | |
| SCHEMBL3963993 | 0.58 | KDM4C (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 611 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3558310-B1 | HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2024-01-17 | — | — | EP | claimed |
| CN-111740024-B | organic light emitting device | 三星显示有限公司 | 2023-08-25 | — | — | CN | claimed |
| EP-4185588-A1 | 3-(1H-IMIDAZOL-2-YL)-2,3,8,8A-TETRAHYDROINDOLIZIN-5(1H)-ONE DERIVATIVES USEFUL AS FACTOR XIA INHIBITORS | Janssen Pharmaceutica NV (BE) | 2023-05-31 | — | — | EP | claimed |
| EP-3558307-B1 | 6,6-FUSED HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME LLC (US) | 2023-05-03 | — | — | EP | claimed |
| CN-111653677-B | Organic light emitting device | 三星显示有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-114920746-A | BTK (BTK inhibitory or degrading agent) and application thereof in medicine | 四川海思科制药有限公司 | 2022-08-19 | — | — | CN | claimed |
| CN-114751859-A | Cyclopentapyridine compound and preparation method and application thereof | 天津中医药大学 | 2022-07-15 | — | — | CN | claimed |
| US-11319298-B2 | Heteroaryl piperidine ether allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2022-05-03 | — | — | US | claimed |
| US-11230556-B2 | 6,5-fused heteroaryl piperidine ether allosteric modulators of the M4 muscarinic acetylcholine receptor | MERCK SHARP & DOHME CORP. (US) | 2022-01-25 | — | — | US | claimed |
| EP-3558306-B1 | 6,5-FUSED HETEROARYL PIPERIDINE ETHER ALLOSTERIC MODULATORS OF THE M4 MUSCARINIC ACETYLCHOLINE RECEPTOR | MERCK SHARP & DOHME (US) | 2021-07-07 | — | — | EP | claimed |
| EP-1021410-B1 | PROSTAGLANDIN AGONISTS AND THEIR USE TO TREAT BONE DISORDERS | PFIZER (US) | 2006-12-27 | — | — | EP | claimed |
| US-20050085517-A1 | Novel amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative | LES LABORATOIRES SERVIER (FR) | 2005-04-21 | — | — | US | claimed |
| US-20030078261-A1 | Prostaglandin agonists | CAMERON KIMBERLY O (US) | 2003-04-24 | — | — | US | claimed |
| EP-1065206-B1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER (US) | 2002-10-09 | — | — | EP | claimed |
| EP-0848000-B1 | Pharmaceutical pyridine derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO (JP) | 2002-06-12 | — | — | EP | claimed |
| EP-1065206-A1 | Tetrazolylalkyl indole compounds as anti-inflammatory and analgesic agents | PFIZER INC. (US) | 2001-01-03 | — | — | EP | claimed |
| US-5965730-A | SELECTIVE PHOSPHODIESTEARASE IV INHIBITOR HAVING BRONCHODIALATION AND ANTI-INFLAMMATORY ACTIVITY; PROPHYLAXIS AND TREATMENT OF ASTHMA | TANABE SEIYAKU CO., LTD. (JP) | 1999-10-12 | — | — | US | claimed |
| EP-0848000-A1 | Pharmaceutical pyridine derivatives, processes for preparing the same and intermediates therefor | TANABE SEIYAKU CO., LTD. (JP) | 1998-06-17 | — | — | EP | claimed |
| EP-0748805-B1 | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor, and pharmaceutical compositions comprising them | TANABE SEIYAKU CO (JP) | 1998-04-08 | — | — | EP | claimed |
| EP-0748805-A1 | Naphthalene derivatives, process for the preparation thereof, and intermediates therefor, and pharmaceutical compositions comprising them | TANABE SEIYAKU CO., LTD. (JP) | 1996-12-18 | — | — | EP | claimed |