Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.30 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL630634 | 0.71 | HDAC6 (0.41) | HDAC1HDAC6AURKAKDR | |
| Hydrochloric Acid SCHEMBL7988951 | 0.68 | HDAC6 (0.40) | HDAC1HDAC6AURKAKDR | |
| SCHEMBL496792 | 0.67 | HDAC1 (0.31) | HDAC1HDAC6 | |
| SCHEMBL3963993 | 0.65 | KDM4C (0.31) | HDAC1HDAC6 | |
| SCHEMBL1327552 | 0.65 | HDAC1 (0.30) | HDAC1HDAC6 | |
| SCHEMBL451027 | 0.65 | KDM4C (0.34) | HDAC1HDAC6AURKAKDR | |
| SCHEMBL15987732 | 0.64 | — | — | |
| SCHEMBL9419852 | 0.64 | HDAC6 (0.57) | HDAC1HDAC6AURKAKDR | |
| SCHEMBL2696780 | 0.64 | KDM4C (0.30) | — | |
| SCHEMBL15987321 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230103984-A1 | Lyotropic Gyroid Mesophase Compositions, Polymer Compositions Comprising the Same, Methods of Preparation Thereof, and Methods of Using the Same | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2023-04-06 | — | — | US | disclosed |
| US-20230096016-A1 | NETWORK TOUGHENING OF ADDITIVELY MANUFACTURED, HIGH GLASS TRANSITION TEMPERATURE MATERIALS VIA SEQUENTIALLY CURED, INTERPENETRATING POLYMERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2023-03-30 | — | — | US | disclosed |
| US-9920145-B2 | Tackifier compounds and methods of using the same | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| US-20170226243-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | UNIV IOWA STATE RES FOUND INC (US) | 2017-08-10 | — | — | US | disclosed |
| US-9688794-B2 | Tackifier compounds and methods of using the same | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2017-06-27 | — | — | US | disclosed |
| US-9481659-B2 | Selective heterocyclic sphingosine 1 phosphate receptor modulators | CELGENE INTERNATIONAL II SÀRL (CH) | 2016-11-01 | — | — | US | disclosed |
| US-9474755-B2 | GLP-1 receptor modulators | CELGENE INTERNATIONAL II SARL (CH) | 2016-10-25 | — | — | US | disclosed |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | RECEPTOS LLC | 2016-02-11 | — | — | US | disclosed |
| US-20150299179-A1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | RECEPTOS, INC. (US) | 2015-10-22 | — | — | US | disclosed |
| US-20150274861-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. | 2015-10-01 | — | — | US | disclosed |
| US-7879968-B2 | Polymer compositions and golf balls with reduced yellowing | TAYLOR MADE GOLF COMPANY, INC. (US) | 2011-02-01 | — | — | US | disclosed |
| EP-2273882-A1 | BIOACTIVE COMPOUNDS FOR TREATMENT OF CANCER AND NEURODEGENERATIVE DISEASES | Poniard Pharmaceuticals, Inc. (US) | 2011-01-19 | — | — | EP | disclosed |
| US-7872052-B2 | Use of heterocyclic compounds as SCCE inhibitors | AREXIS AB (SE) | 2011-01-18 | — | — | US | disclosed |
| US-20090325889-A1 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | CAMPBELL DAVID ALAN | 2009-12-31 | — | — | US | disclosed |
| US-20070142568-A1 | Polymer compositions comprising peptizers, sports equipment comprising such compositions, and method for their manufacture | TAYLOR MADE GOLF COMPANY, INC. | 2007-06-21 | — | — | US | disclosed |
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | ARPIDA A/S (DK) | 2007-03-22 | — | — | US | disclosed |
| US-7115624-B1 | Method of inhibiting protein tyrosine phosphatase 1B and/or T-cell protein tyrosine phosphatase 4 and/or other PTPases with an Asp residue at position 48 | NOVO NORDISK A/S (DK) | 2006-10-03 | — | — | US | disclosed |
| US-20040110929-A1 | TF binding compound | NOVO NORDISK A/S (DK) | 2004-06-10 | — | — | US | disclosed |
| US-5591862-A | ANTILIPEMICS, TREATING DIABETES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-01-07 | — | — | US | disclosed |
| EP-0629624-A1 | Tetrazole derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274861-A1 | TACKIFIER COMPOUNDS AND METHODS OF USING THE SAME | ORC3, OR10J3, NR2C2 | HDAC1 1423/4885HDAC6 2406/4885AURKA 827/4885 |
| US-20150299179-A1 | SELECTIVE HETEROCYCLIC SPHINGOSINE 1 PHOSPHATE RECEPTOR MODULATORS | S1PR1, S1PR3, S1PR2 | HDAC1 2030/4885HDAC6 2828/4885AURKA 4466/4885 |
| US-20090325889-A1 | HEPATITIS C SERINE PROTEASE INHIBITORS AND USES THEREFOR | PREP, HPN, PRSS1 | HDAC1 2178/4885HDAC6 3199/4885AURKA 4403/4885 |
| US-20070066672-A1 | Benzimidazole derivatives and use thereof as peptide deformylase inhibitors | PDF, MRPL21, PEPD | HDAC1 567/4885HDAC6 12/4885AURKA 1942/4885 |
| US-20160038487-A1 | NOVEL GLP-1 RECEPTOR MODULATORS | GLP1R, GIPR, NPY1R | HDAC1 2685/4885HDAC6 3369/4885AURKA 4750/4885 |
| US-20230103984-A1 | Lyotropic Gyroid Mesophase Compositions, Polymer Compositions Comprising the Same, Methods of Preparation Thereof, and Methods of Using the Same | MCM2, TOP2A, BLM | HDAC1 4202/4885HDAC6 4604/4885AURKA 1158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.