SCHEMBL17252596

SCHEMBL17252596

c1ccc(-c2cc(-c3ccccc3)cc(-c3nc(-c4cc(-c5ccccc5)cc(-c5ccccc5)c4)nc(-c4cccc5oc6ccc(-c7ccc8c(c7)c7ccccc7n8-c7ccccc7)cc6c45)n3)c2)cc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PLA2G2A P14555 3/20 0.35
PLA2G4A P47712 3/20 0.35
PLA2G10 O15496 1/20 0.35
PTGER4 P35408 1/20 0.34
HPSE Q9Y251 2/20 0.33
SIRT2 Q8IXJ6 1/20 0.32
SIRT1 Q96EB6 1/20 0.32
PRKDC P78527 1/20 0.32
PIM1 P11309 1/20 0.32
CSNK2A2 P19784 1/20 0.32
CSNK2B P67870 1/20 0.32
PIM3 Q86V86 1/20 0.32
PIM2 Q9P1W9 1/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17252785 1.00 KDM4E (0.36) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17252790 0.99 KDM4E (0.35) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17252572 0.99 KDM4E (0.35) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17252563 0.98 KDM4E (0.36) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL22257774 0.98 KDM4E (0.36) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL17252458 0.98 KDM4E (0.38) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL23559257 0.97 KDM4E (0.35) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL22145909 0.97 KDM4E (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL22145906 0.97 KDM4E (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A
SCHEMBL22258082 0.97 KDM4E (0.37) KDM4EATML3MBTL1PLA2G2APLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11877511-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-11877511-B2 Materials for organic light emitting devices MERCK PATENT GMBH (DE) 2024-01-16 US disclosed
US-20230138502-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-05-04 US disclosed
US-20230138502-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-05-04 US disclosed
US-20230125939-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-04-27 US disclosed
US-20230125939-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2023-04-27 US disclosed
US-20200251660-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2020-08-06 US disclosed
EP-3140302-B1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2019-08-21 EP disclosed
US-20170186965-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2017-06-29 US disclosed
US-20170186965-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2017-06-29 US disclosed
WO-2015169412-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES MERCK PATENT GMBH (DE) 2015-11-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170186965-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA KDM4E 3065/4885ATM 4454/4885L3MBTL1 565/4885
US-20230125939-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA KDM4E 3065/4885ATM 4454/4885L3MBTL1 565/4885
US-20230138502-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA KDM4E 3065/4885ATM 4454/4885L3MBTL1 565/4885
US-20200251660-A1 MATERIALS FOR ORGANIC LIGHT EMITTING DEVICES DDT, ESD, ETFA KDM4E 3065/4885ATM 4454/4885L3MBTL1 565/4885
US-11877511-B2 Materials for organic light emitting devices DDT, ESD, ETFA KDM4E 3065/4885ATM 4454/4885L3MBTL1 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.