Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 2/20 | 0.46 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15720308 | 0.83 | DGAT1 (0.49) | DGAT1USP30FFAR1GSK3AGSK3B | |
| SCHEMBL30658717 | 0.82 | USP30 (0.56) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL1912346 | 0.82 | USP30 (0.56) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL1180889 | 0.79 | USP30 (0.50) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL799138 | 0.79 | USP30 (0.53) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL1180976 | 0.79 | AAK1 (0.47) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL17253108 | 0.79 | DGAT1 (0.41) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL21199515 | 0.78 | DGAT1 (0.43) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL31583730 | 0.78 | FFAR1 (0.40) | DGAT1USP30AAK1FFAR1PRMT5 | |
| SCHEMBL17654360 | 0.77 | AAK1 (0.50) | DGAT1USP30AAK1FFAR1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134629-A1 | NUCLEAR TRANSPORT REGULATOR AND USE THEREOF | 上海海雁医药科技有限公司 | 2023-07-20 | — | — | WO | disclosed |
| WO-2015170775-A1 | SUBSTITUTED AZOLE COMPOUND AND THERAPEUTIC AGENT FOR DIABETES | 日産化学工業株式会社 | 2015-11-12 | — | — | WO | disclosed |