Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 2/20 | 0.30 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1725334 | 1.00 | PLAU (0.39) | PLAUALDH1A1GAAMPLSMN1; SMN2 | |
| SCHEMBL1726524 | 0.74 | IRAK4 (0.44) | — | |
| SCHEMBL3713462 | 0.74 | L3MBTL1 (0.38) | PLAUALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL3713461 | 0.74 | L3MBTL1 (0.38) | PLAUALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL13187662 | 0.72 | L3MBTL1 (0.45) | PLAUALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL1727214 | 0.70 | STK17B (0.38) | PLAUALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL1727216 | 0.70 | STK17B (0.38) | PLAUALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL13187666 | 0.70 | STK17B (0.38) | PLAUALDH1A1GAASMN1; SMN2KDM4E | |
| SCHEMBL1725825 | 0.70 | TDP1 (0.38) | PLAUALDH1A1SMN1; SMN2KDM4EKMT2A | |
| SCHEMBL1725824 | 0.70 | TDP1 (0.38) | PLAUALDH1A1SMN1; SMN2KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403849-A1 | OXAZOLE PYRIDINE DERIVATIVES USEFUL AS S1P1 RECEPTOR AGONISTS | Merck Serono S.A. (CH) | 2012-01-11 | — | — | EP | disclosed |