Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.58 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685347 | 1.00 | MC4R (0.58) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL9356274 | 0.83 | MC4R (0.56) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL9356266 | 0.83 | MC4R (0.56) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL9356279 | 0.83 | MC4R (0.56) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL30254694 | 0.82 | MC4R (0.55) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL25111799 | 0.81 | CTSC (0.59) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| Hydrochloric Acid SCHEMBL15142852 | 0.81 | MC4R (0.54) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL18576456 | 0.81 | CTSC (0.59) | MC4RCACNA1GALDH1A1HPGDUSP2 | |
| SCHEMBL14963192 | 0.79 | MC4R (0.68) | MC4RALDH1A1HPGDUSP2TSHR | |
| SCHEMBL19715630 | 0.79 | MC4R (0.68) | MC4RALDH1A1HPGDUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |