Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18057428 | 1.00 | DPP4 (0.44) | DPP4CYP3A4KDM4EALDH1A1HPGD | |
| SCHEMBL22348882 | 0.88 | DPP4 (0.46) | DPP4CYP3A4KDM4EALDH1A1HPGD | |
| SCHEMBL17254932 | 0.86 | DPP4 (0.47) | DPP4CYP3A4 | |
| SCHEMBL23160976 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL18057418 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL18057422 | 0.84 | KDM4E (0.41) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL18042618 | 0.83 | NCF1 (0.43) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL18042600 | 0.82 | KDM4E (0.46) | KDM4EALDH1A1HPGDGAATSHR | |
| SCHEMBL18042639 | 0.82 | NCF1 (0.58) | DPP4KDM4EALDH1A1HPGDGAA | |
| SCHEMBL18059235 | 0.82 | KDM4E (0.43) | KDM4EALDH1A1HPGDGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015172123-A1 | NOVEL COMPOSITIONS, USES AND METHODS FOR MAKING THEM | HADDACH MUSTAPHA (US) | 2015-11-12 | — | — | WO | disclosed |