Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2221282 | 0.88 | TSHR (0.41) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL26126222 | 0.87 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL26126226 | 0.87 | SMN1; SMN2 (0.53) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL1421483 | 0.84 | MAPK1 (0.60) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL3493429 | 0.83 | MAPK1 (0.43) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL2216016 | 0.82 | POLB (0.43) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL3492252 | 0.81 | POLB (0.45) | TSHRSMN1; SMN2MAPK1HPGDRECQL | |
| SCHEMBL3716685 | 0.81 | HPGD (0.58) | TSHRSMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL3725686 | 0.81 | HPGD (0.64) | TSHRSMN1; SMN2HPGDHTTALDH1A1 | |
| SCHEMBL3854537 | 0.80 | PRMT5 (0.40) | TSHRSMN1; SMN2MAPK1HPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2944637-B1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM CORP (JP) | 2020-02-19 | — | — | EP | disclosed |
| EP-2944637-A1 | NITROGEN-CONTAINING HETEROCYLIC COMPOUND OR SALT THEREOF | FUJIFILM Corporation (JP) | 2015-11-18 | — | — | EP | disclosed |