Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 19/20 | 0.49 |
| ▸ | KDR | P35968 | 5/20 | 0.48 |
| ▸ | AXL | P30530 | 4/20 | 0.45 |
| ▸ | RET | P07949 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | KIT | P10721 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 2/20 | 0.44 |
| ▸ | PLK4 | O00444 | 1/20 | 0.44 |
| ▸ | STK25 | O00506 | 1/20 | 0.44 |
| ▸ | CIT | O14578 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.44 |
| ▸ | MUSK | O15146 | 1/20 | 0.44 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.44 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.44 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255604 | 1.00 | MET (0.49) | METKDRAXLRETPDGFRB | |
| SCHEMBL17255608 | 0.92 | MET (0.48) | METKDRAXLRETPDGFRB | |
| SCHEMBL372086 | 0.89 | MET (0.53) | METKDRAXLRETPDGFRB | |
| SCHEMBL15918171 | 0.87 | MET (0.51) | METKDRAXLRETPDGFRB | |
| SCHEMBL15918293 | 0.87 | MET (0.51) | METKDRAXLRETPDGFRB | |
| SCHEMBL25188193 | 0.86 | MET (0.52) | METKDRAXLRETPDGFRB | |
| SCHEMBL29991083 | 0.86 | MET (0.52) | METKDRAXLRETPDGFRB | |
| Hydrochloric Acid SCHEMBL15918382 | 0.85 | MET (0.53) | METKDRAXLRETPDGFRB | |
| Hydrochloric Acid SCHEMBL15918137 | 0.85 | MET (0.53) | METKDRAXLRETPDGFRB | |
| Hydrochloric Acid SCHEMBL15918224 | 0.85 | MET (0.53) | METKDRAXLRETPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669289-B1 | PHOSPHORUS SUBSTITUTED GROUP-CONTAINING QUINOLINE-LIKE COMPOUND, ITS PREPARATION PROCESS, MEDICAL COMPOSITION CONTAINING THE COMPOUND AND APPLICATION | BEIJING KONRUNS PHARMACEUTICAL CO LTD (CN) | 2015-11-18 | — | — | EP | claimed |