Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | GAA | P10253 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.43 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17255695 | 0.87 | KDM4E (0.66) | KDM4EGAAMAPK1ALDH1A1TSHR | |
| SCHEMBL28171784 | 0.83 | KDM4E (0.51) | KDM4EGAAALDH1A1TSHRMAPT | |
| SCHEMBL15443102 | 0.83 | KDM4E (0.70) | KDM4EGAAALDH1A1TSHRMAPT | |
| SCHEMBL15330995 | 0.81 | KDM4E (0.49) | KDM4EGAAMAPK1ALDH1A1TSHR | |
| SCHEMBL17255680 | 0.80 | KDM4E (0.66) | KDM4EGAAMAPK1TSHRMAPT | |
| SCHEMBL3685546 | 0.79 | KDM4E (0.51) | KDM4EGAATSHRMAPTNPC1 | |
| SCHEMBL15442925 | 0.78 | POLB (0.49) | KDM4EGAAMAPK1ALDH1A1TSHR | |
| SCHEMBL2052349 | 0.77 | KDM4E (0.67) | KDM4EGAAMAPK1ALDH1A1TSHR | |
| SCHEMBL15442244 | 0.77 | KDM4E (0.85) | KDM4EGAAALDH1A1TSHRMAPT | |
| SCHEMBL15443120 | 0.77 | KDM4E (0.71) | KDM4EGAAALDH1A1TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2669274-B1 | TOPICAL ANTIFUNGAL AGENT | MEIJI SEIKA PHARMA CO LTD (JP) | 2015-11-18 | — | — | EP | claimed |
| CN-103339112-A | Topical antifungal agent | MEIJI SEIKA PHARMA CO LTD | 2013-10-02 | — | — | CN | claimed |
| CN-103339112-A | Topical antifungal agent | MEIJI SEIKA PHARMA CO LTD | 2013-10-02 | — | — | CN | disclosed |