SCHEMBL2052349

SCHEMBL2052349

Cc1cc(C)n(-c2ccccc2O)n1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.67
GAA P10253 1/20 0.67
ADORA2A P29274 1/20 0.49
TSHR P16473 2/20 0.49
LMNA P02545 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
MEN1 O00255 2/20 0.46
MAPK1 P28482 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
XBP1 P17861 1/20 0.46
NTSR1 P30989 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
POLB P06746 2/20 0.44
ALDH1A1 P00352 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL17255684 0.93 KDM4E (0.59) KDM4EGAAADORA2ATSHRLMNA
SCHEMBL17255679 0.86 KDM4E (0.62) KDM4EGAAADORA2ATSHRLMNA
SCHEMBL17255733 0.85 KDM4E (0.47) KDM4EGAAADORA2ALMNASMN1; SMN2
Hydrochloric Acid SCHEMBL4336653 0.82 KDM4E (0.64) KDM4EGAATSHRLMNASMN1; SMN2
Hydrochloric Acid SCHEMBL4336655 0.82 KDM4E (0.64) KDM4EGAATSHRLMNASMN1; SMN2
Phenol SCHEMBL4337822 0.82 KDM4E (0.58) KDM4EGAATSHRLMNASMN1; SMN2
SCHEMBL15443102 0.80 KDM4E (0.70) KDM4EGAAADORA2ATSHRLMNA
SCHEMBL17255685 0.80 KDM4E (0.70) KDM4EGAAADORA2ATSHRLMNA
SCHEMBL17545844 0.80 KDM4E (0.70) KDM4EGAAADORA2ATSHRLMNA
SCHEMBL17255714 0.79 KDM4E (0.58) KDM4EGAAADORA2ATSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10123978-B2 Patch for treating dermatophytosis MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-11-13 US disclosed
EP-2881114-B1 ANTI-TRICHOPHYTIC ADHESIVE PATCH MEIJI SEIKA PHARMA CO LTD (JP) 2018-09-05 EP disclosed
US-20180200199-A1 PATCH FOR TREATING DERMATOPHYTOSIS MEIJI SEIKA PHARMA CO., LTD. (JP) 2018-07-19 US disclosed
EP-2669274-B1 TOPICAL ANTIFUNGAL AGENT MEIJI SEIKA PHARMA CO LTD (JP) 2015-11-18 EP disclosed
CN-103339112-B Topical antifungal agents MEIJI SEIKA PHARMA CO.,LTD. (JP) 2015-08-12 CN disclosed
US-20150209301-A1 PATCH FOR ANTI-DERMATOPHYTOSIS NICHIBAN COMPANY LIMITED (JP) 2015-07-30 US disclosed
EP-2889031-A1 ANTITRICHOPHYTOSIS SOLUTION FOR EXTERNAL USE Meiji Seika Pharma Co., Ltd. (JP) 2015-07-01 EP disclosed
EP-2881114-A1 ANTI-TRICHOPHYTIC ADHESIVE PATCH Meiji Seika Pharma Co., Ltd. (JP) 2015-06-10 EP disclosed
CN-104661661-A External liquid preparation for resisting trichophytosis MEIJI SEIKA PHARMA CO LTD 2015-05-27 CN disclosed
US-8889727-B2 Topical antifungal agent MEIJI SEIKA PHARMA CO., LTD. (JP) 2014-11-18 US disclosed
US-7608563-B2 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same MITSUI AGRO CHEMICALS, INC. (JP) 2009-10-27 US disclosed
EP-1426365-B9 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME MITSUI CHEMICALS AGRO INC (JP) 2009-10-21 EP disclosed
EP-1426365-B1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME SANKYO AGRO CO LTD (JP) 2009-07-15 EP disclosed
CN-101068803-A Biaryloxymethylarene carboxylic acid compounds HOFFMANN LA ROCHE (CH) 2007-11-07 CN disclosed
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same SANKYO AGRO COMPANY, LIMITED (JP) 2005-02-17 US disclosed
CN-1543455-A 3-phenoxy-4-pyridazinol derivatives and herbicidal compositions containing the same 三共农业株式会社 2004-11-03 CN disclosed
EP-1426365-A1 3-PHENOXY-4-PYRIDAZINOL DERIVATIVE AND HERBICIDE COMPOSITION CONTAINING THE SAME Sankyo Agro Company, Limited (JP) 2004-06-09 EP disclosed
US-4514214-A Herbicidal sulfamates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-30 US disclosed
US-4475944-A PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-09 US disclosed
EP-0096593-A2 Herbicidal sulfamates E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-12-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180200199-A1 PATCH FOR TREATING DERMATOPHYTOSIS DPM1, KRT18, LCP1 KDM4E 159/4885GAA 4547/4885ADORA2A 4148/4885
US-10123978-B2 Patch for treating dermatophytosis DPM1, KRT18, LCP1 KDM4E 159/4885GAA 4547/4885ADORA2A 4148/4885
US-20150209301-A1 PATCH FOR ANTI-DERMATOPHYTOSIS CUTA, NACA, POLR1C KDM4E 1955/4885GAA 4680/4885ADORA2A 3056/4885
US-20050037925-A1 3-phenoxy-4-pyridazinol derivatives and herbicide composition containing the same CBR3, DDT, CHRM2 KDM4E 960/4885GAA 3492/4885ADORA2A 3318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.