SCHEMBL1725751

SCHEMBL1725751

COc1ccc(N(CCCF)S(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCNCC1

nearest known ligand 0.45

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 19/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1613030 0.99 HTR6 (0.44) HTR6
SCHEMBL1725822 0.92 HTR6 (0.46) HTR6
Hydrochloric Acid SCHEMBL1611764 0.91 HTR6 (0.46) HTR6
SCHEMBL1612610 0.86 MAPT (0.39)
SCHEMBL1726886 0.85 HTR6 (0.51) HTR6
SCHEMBL614842 0.85 HTR6 (0.45) HTR6
Hydrochloric Acid SCHEMBL1611891 0.85 HTR6 (0.51) HTR6
Hydrochloric Acid SCHEMBL614803 0.84 HTR6 (0.44) HTR6
SCHEMBL617277 0.83 ESR1 (0.46) HTR6
Hydrochloric Acid SCHEMBL618220 0.82 HTR6 (0.46) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011163279-A3 LOW-POWER WIRELESSLY-LINKED RFID TRACKING SYSTEM ROSE MARK D (US) 2012-05-10 WO claimed
EP-2217583-B1 BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR ABBOTT GMBH & CO KG (DE) 2011-11-30 EP claimed