SCHEMBL1725852

SCHEMBL1725852

NP(N)(=O)NS(=O)(=O)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA2 P00918 5/20 0.42
CA1 P00915 2/20 0.42
CA7 P43166 1/20 0.36
CA13 Q8N1Q1 1/20 0.36
EPHX1 P07099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29691004 0.84 CA2 (0.42) CA2CA1CA7CA13EPHX1
SCHEMBL12247858 0.78 CA2 (0.46) CA2CA1CA7CA13EPHX1
SCHEMBL10531545 0.77 CA2 (0.40) CA2CA1CA7CA13
SCHEMBL19130433 0.76 CA1 (0.43) CA2CA1CA7CA13EPHX1
SCHEMBL12247862 0.74 CA1 (0.42) CA2CA1CA7CA13EPHX1
SCHEMBL12247859 0.74 CA1 (0.42) CA2CA1CA7CA13EPHX1
SCHEMBL28435208 0.74 CA1 (0.48) CA2CA1CA7CA13EPHX1
SCHEMBL10530304 0.74 CA1 (0.43) CA2CA1
SCHEMBL10531548 0.73 CA2 (0.37) CA2CA1CA7CA13
SCHEMBL11057093 0.73 CA1 (0.37) CA2CA1CA7CA13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2802560-B1 PROCESS FOR THE ASYMMETRIC OXIDATION OF ORGANIC COMPOUNDS WITH PEROXIDES IN THE PRESENCE OF A CHIRAL ACID CATALYST STUDIENGESELLSCHAFT KOHLE MBH (DE) 2018-03-07 EP claimed
EP-2403842-B1 CHIRAL DISULFONIMIDES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2016-06-29 EP disclosed
CN-105111228-A Chiral phosphoric acid with 5,5'-bitetralone skeleton and preparation method thereof NANJING UNIVERSITY OF TECHNOLOGY 2015-12-02 CN disclosed
US-9079869-B2 Chiral disulfonimides STUDIENGESELLSCHAFT KOHLE MBH (DE) 2015-07-14 US disclosed
EP-2403842-A1 CHIRAL DISULFONIMIDES Studiengesellschaft Kohle MbH (DE) 2012-01-11 EP disclosed
US-20110313150-A1 CHIRAL DISULFONIMIDES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2011-12-22 US disclosed
WO-2010099786-A1 CHIRAL DISULFONIMIDES STUDIENGESELLSCHAFT KOHLE MBH (DE) 2010-09-10 WO disclosed
US-4824783-A FERTILIZERS ENICHEM S.P.A. (IT) 1989-04-25 US disclosed
US-4696693-A Oxidized sulfur derivatives of diaminophosphinyl compounds as urease inhibitors and urease inhibited urea based fertilizer compositions ALLIED CORPORATION (US) 1987-09-29 US disclosed
US-4629491-A PLANT GROWTH REGULATORS ALLIED CORPORATION (US) 1986-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110313150-A1 CHIRAL DISULFONIMIDES STS, SUDS3, SF1 CA2 120/4885CA1 20/4885CA7 56/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.