SCHEMBL1725866

SCHEMBL1725866

COc1ccc(NS(=O)(=O)c2cccc(OC(F)F)c2)cc1N1CCNCC1

nearest known ligand 0.71

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 20/20 0.71

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1611917 0.99 HTR6 (0.70) HTR6
SCHEMBL7898337 0.96 HTR6 (0.67) HTR6
Hydrochloric Acid SCHEMBL3724202 0.96 HTR6 (0.66) HTR6
SCHEMBL615949 0.93 HTR6 (0.71) HTR6
Hydrochloric Acid SCHEMBL615097 0.92 HTR6 (0.70) HTR6
SCHEMBL1613097 0.90 HTR6 (0.71) HTR6
SCHEMBL1725962 0.89 HTR6 (0.73) HTR6
SCHEMBL1611972 0.89 HTR6 (0.56) HTR6
SCHEMBL6736311 0.89 HTR6 (0.55) HTR6
Hydrochloric Acid SCHEMBL1613077 0.89 HTR6 (0.71) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011163279-A3 LOW-POWER WIRELESSLY-LINKED RFID TRACKING SYSTEM ROSE MARK D (US) 2012-05-10 WO claimed
EP-2217583-B1 BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR ABBOTT GMBH & CO KG (DE) 2011-11-30 EP claimed