SCHEMBL172590

SCHEMBL172590

CC(F)c1ccccc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19219865 1.00
SCHEMBL18656958 1.00
Bicarbonate SCHEMBL28309384 0.89 CYP2D6 (0.48)
SCHEMBL16426382 0.84 PTGS2 (0.54)
SCHEMBL5149720 0.83 ESR1 (0.38)
SCHEMBL23315087 0.77 TAAR1 (0.42)
SCHEMBL10338130 0.77 TAAR1 (0.42)
SCHEMBL1030082 0.77 TAAR1 (0.42)
SCHEMBL15199514 0.77 TAAR1 (0.44)
SCHEMBL10039362 0.75 TYR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 167 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240343695-A1 Lysophosphatidic Acid Receptor 1 Antagonists as Migrastatics for Cancer LAKEHEAD UNIVERSITY (CA) 2024-10-17 US claimed
US-20240317709-A1 Lysophosphatidic Acid Receptor Antagonists for Breast Cancer Treatment UNIV LAKEHEAD (CA) 2024-09-26 US claimed
CN-116058379-A Pesticide composition containing fluorine-containing compound synthesized by photocatalysis method and application thereof 华南农业大学 2023-05-05 CN claimed
CN-104937457-B Wide-viewing-angle optical film with reverse wavelength dispersion 阿克隆聚合物系统有限公司 2019-01-25 CN claimed
EP-0409368-B1 SUBSTITUTED ALFA PYRIMIDINYLOXY CARBOXYLIC ACID DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS AN AGENT WITH HERBICIDAL, FUNGICIDAL AND PLANTGROWTH REGULATING ACTIVITY SCHERING AKTIENGESELLSCHAFT (DE) 1992-11-11 EP claimed
CN-119980266-A Method for electrochemical catalysis of direct amination reaction of aromatic alkane hydrocarbon bond 南京工业大学 2025-05-13 CN disclosed
CN-119613341-A Imidazole zwitterionic compound, preparation method thereof and application in battery 珠海市赛纬电子材料股份有限公司 2025-03-14 CN disclosed
CN-116640072-B Method for synthesizing oxime compound by catalyzing hydrocarbon bond oxidation through tetradentate nitrogen-containing coordination manganese 陕西师范大学 2025-02-28 CN disclosed
US-20240343695-A1 Lysophosphatidic Acid Receptor 1 Antagonists as Migrastatics for Cancer LAKEHEAD UNIVERSITY (CA) 2024-10-17 US disclosed
US-20240317709-A1 Lysophosphatidic Acid Receptor Antagonists for Breast Cancer Treatment UNIV LAKEHEAD (CA) 2024-09-26 US disclosed
CN-118299656-A Electrolyte, secondary battery and device 蔚来电池科技(安徽)有限公司 2024-07-05 CN disclosed
CN-117924177-A Preparation method of pazopanib intermediate 2, 3-dimethyl-6-amino-2H-indazole and analogues thereof 南京杰运医药科技有限公司 2024-04-26 CN disclosed
US-5811439-A ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS SENGA PHARMACEUTICAL LABORATORY INC. (JP) 1998-09-22 US disclosed
EP-0780389-A1 Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them TOBISHI PHARMACEUTICAL CO., LTD. (JP) 1997-06-25 EP disclosed
EP-0409025-A2 N-[Indol-6-yl]-heterocyclic compounds BAYER AG (DE) 1991-01-23 EP disclosed
CN-1036029-A Supertwist-liquid-crystal display (element) MERCK PATENT GMBH (DE) 1989-10-04 CN disclosed
EP-0319471-A2 Resolution process CIBA-GEIGY AG (CH) 1989-06-07 EP disclosed
EP-0017455-B1 LINEAR CRYSTALLINE ALPHA-ALKYLPOLYBENZYLS AND PROCESS FOR PREPARING THEM EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-04-13 EP disclosed
US-4259475-A FRIEDEL-CRAFTS COMPLEX CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1981-03-31 US disclosed
EP-0017455-A1 Linear crystalline alpha-alkylpolybenzyls and process for preparing them EXXON RESEARCH AND ENGINEERING COMPANY (US) 1980-10-15 EP disclosed