⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17259206 | 1.00 | — | — | |
| SCHEMBL17259205 | 1.00 | — | — | |
| SCHEMBL1010887 | 0.81 | CTSD (0.31) | — | |
| Hydrochloric Acid SCHEMBL30992347 | 0.79 | CTSD (0.30) | — | |
| SCHEMBL2186219 | 0.79 | — | — | |
| SCHEMBL18055668 | 0.79 | — | — | |
| SCHEMBL20497902 | 0.79 | — | — | |
| SCHEMBL15914028 | 0.79 | — | — | |
| SCHEMBL1317745 | 0.79 | — | — | |
| SCHEMBL15914026 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209537-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION | 2019-07-11 | — | — | US | disclosed |
| US-20150329534-A1 | THIAZOLECARBOXAMIDES AND PYRIDINECARBOXAMIDE COMPOUNDS USEFUL AS PIM KINASE INHIBITORS | INCYTE CORPORATION | 2015-11-19 | — | — | US | disclosed |