Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.48 |
| ▸ | DRD3 | P35462 | 2/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1612055 | 0.99 | HTR6 (0.47) | HTR6HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1726322 | 0.88 | HTR6 (0.46) | HTR6HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1612196 | 0.88 | HTT (0.41) | KDM2BESR1MEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL1611755 | 0.87 | HTR6 (0.46) | HTR6HTR1AHTR2AHTR2CHTR7 | |
| SCHEMBL1725822 | 0.83 | HTR6 (0.46) | HTR6KDM2B | |
| SCHEMBL617277 | 0.83 | ESR1 (0.46) | HTR6ESR1 | |
| Hydrochloric Acid SCHEMBL1611764 | 0.83 | HTR6 (0.46) | HTR6KDM2B | |
| Hydrochloric Acid SCHEMBL618220 | 0.82 | HTR6 (0.46) | HTR6ESR1 | |
| SCHEMBL615215 | 0.82 | HTR6 (0.52) | HTR6 | |
| SCHEMBL1613165 | 0.81 | HTT (0.40) | HTR6HTR1AHTR2AHTR2CHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011163279-A3 | LOW-POWER WIRELESSLY-LINKED RFID TRACKING SYSTEM | ROSE MARK D (US) | 2012-05-10 | — | — | WO | claimed |
| EP-2217583-B1 | BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR | ABBOTT GMBH & CO KG (DE) | 2011-11-30 | — | — | EP | claimed |