SCHEMBL1726110

SCHEMBL1726110

COc1ccc(S(=O)(=O)Nc2ccc(OC)c(N3CCNCC3)c2)cc1OC(F)F

nearest known ligand 0.70

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 20/20 0.70
HTR7 P34969 1/20 0.56
HTR4 Q13639 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1610581 0.99 HTR6 (0.68) HTR6HTR7HTR4
SCHEMBL616962 0.96 HTR6 (0.70) HTR6HTR7HTR4
Hydrochloric Acid SCHEMBL614319 0.95 HTR6 (0.69) HTR6HTR7HTR4
SCHEMBL614721 0.94 HTR6 (0.70) HTR6HTR7HTR4
Hydrochloric Acid SCHEMBL615670 0.93 HTR6 (0.69) HTR6HTR7HTR4
SCHEMBL616914 0.92 HTR6 (0.70) HTR6HTR7HTR4
Hydrochloric Acid SCHEMBL617091 0.91 HTR6 (0.69) HTR6HTR7HTR4
SCHEMBL1725962 0.90 HTR6 (0.73) HTR6HTR7HTR4
SCHEMBL617176 0.89 HTR6 (0.67) HTR6
SCHEMBL617945 0.89 HTR6 (0.61) HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011163279-A3 LOW-POWER WIRELESSLY-LINKED RFID TRACKING SYSTEM ROSE MARK D (US) 2012-05-10 WO claimed
EP-2217583-B1 BENZENESULFONANILIDE COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR ABBOTT GMBH & CO KG (DE) 2011-11-30 EP claimed