Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 7/20 | 0.47 |
| ▸ | PGR | P06401 | 3/20 | 0.47 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1261884 | 0.95 | NR3C1 (0.49) | NR3C1PGRAR | |
| SCHEMBL1261886 | 0.95 | NR3C1 (0.49) | NR3C1PGRAR | |
| SCHEMBL1259936 | 0.85 | NR3C1 (0.58) | NR3C1PGRAR | |
| SCHEMBL1259935 | 0.85 | NR3C1 (0.58) | NR3C1PGRAR | |
| SCHEMBL1261387 | 0.84 | NR3C1 (0.61) | NR3C1PGRAR | |
| SCHEMBL1261386 | 0.84 | NR3C1 (0.61) | NR3C1PGRAR | |
| SCHEMBL3535520 | 0.83 | NR3C1 (0.62) | NR3C1PGRAR | |
| SCHEMBL1260313 | 0.82 | NR3C1 (0.55) | NR3C1PGRAR | |
| SCHEMBL1261434 | 0.82 | NR3C1 (0.55) | NR3C1PGRAR | |
| SCHEMBL1260502 | 0.82 | NR3C1 (0.55) | NR3C1PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1994005-B9 | TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma AG (DE) | 2012-01-11 | — | — | EP | disclosed |
| EP-1994005-B1 | TETRAHYDRONAPHTHALINE DERIVATIVES, METHODS FOR THE PRODUCTION AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | BAYER SCHERING PHARMA AG (DE) | 2011-07-20 | — | — | EP | disclosed |