⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL183214 | 0.86 | — | — | |
| SCHEMBL45858 | 0.86 | — | — | |
| SCHEMBL30704427 | 0.86 | — | — | |
| Hydrochloric Acid SCHEMBL25381774 | 0.83 | CYP2A6 (0.52) | — | |
| SCHEMBL9596839 | 0.80 | CYP2D6 (0.46) | — | |
| SCHEMBL19248476 | 0.80 | TAAR1 (0.44) | — | |
| SCHEMBL10990263 | 0.78 | CYP2C19 (0.48) | — | |
| SCHEMBL19248483 | 0.77 | MEN1 (0.38) | — | |
| SCHEMBL13407748 | 0.76 | — | — | |
| SCHEMBL19248484 | 0.75 | MAOA (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848963-B | Preparation method of flame-retardant resin capable of being repeatedly processed and thermally cured at high temperature | 北京化工大学 | 2022-05-27 | — | — | CN | claimed |
| CN-111848963-A | Preparation method of flame-retardant resin capable of being repeatedly processed and thermally cured at high temperature | 北京化工大学 | 2020-10-30 | — | — | CN | claimed |
| CN-116655476-B | Preparation method of amino alcohol | 北京大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-116655476-A | Preparation method of amino alcohol | 北京大学 | 2023-08-29 | — | — | CN | disclosed |
| CN-111848963-B | Preparation method of flame-retardant resin capable of being repeatedly processed and thermally cured at high temperature | 北京化工大学 | 2022-05-27 | — | — | CN | disclosed |
| WO-2022033548-A1 | IMMUNOREGULATORY COMPOUND AND ANTITUMOR APPLICATION THEREOF | 上海科技大学 | 2022-02-17 | — | — | WO | disclosed |
| CN-111848963-A | Preparation method of flame-retardant resin capable of being repeatedly processed and thermally cured at high temperature | 北京化工大学 | 2020-10-30 | — | — | CN | disclosed |
| US-9988491-B2 | Methods and compounds for producing nylon 6,6 | EMPIRE TECHNOLOGY DEVELOPMENT LLC (US) | 2018-06-05 | — | — | US | disclosed |
| US-9808466-B2 | Macrocyclic compounds as protein kinase inhibitors | FUNDACIÓN CENTRO NACIONAL DE INVESTIGACIONES ONCOLOGICAS CARLOS III | 2017-11-07 | — | — | US | disclosed |
| EP-2316832-B1 | Cyclopamine analogues and methods of use thereof | INFINITY PHARMACEUTICALS INC (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20160296528-A1 | MACROCYCLIC COMPOUNDS AS PROTEIN KINASE INHIBITORS | Fundación Del Sector Público Estatal Centro Nacional De Investigaciones Oncológicas Carlos III (F.S.P. CNIO) (ES) | 2016-10-13 | — | — | US | disclosed |
| US-7691856-B2 | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-04-06 | — | — | US | disclosed |
| US-20090306079-A1 | 3,4-DI-SUBSTITUTED CYCLOBUTENE-1,2-DIONES AS CXC-CHEMOKINE RECEPTOR LIGANDS | SCHERING CORPORATION | 2009-12-10 | — | — | US | disclosed |
| US-20080090823-A1 | THIADIAZOLES AS CXC- AND CC- CHEMOKINE RECEPTOR LIGANDS | MERCK SHARP & DOHME CORP. | 2008-04-17 | — | — | US | disclosed |
| EP-1644320-B1 | INDANE DERIVATES AS MUSCARINIC RECEPTOR AGONISTS | LILLY CO ELI (US) | 2008-01-16 | — | — | EP | disclosed |
| US-20070264230-A1 | Thiadiazoledioxides and thiadiazoleoxides as CXC- and CC-chemokine receptor ligands | SCHERING CORPORATION | 2007-11-15 | — | — | US | disclosed |
| US-7265246-B2 | Indane derivates as muscarinic receptor agonists | ELI LILLY AND COMPANY (US) | 2007-09-04 | — | — | US | disclosed |
| US-20070060587-A1 | Indane derivates as muscarinic receptor agonists | ELI LILLY AND COMPANY (US) | 2007-03-15 | — | — | US | disclosed |
| US-20070021494-A1 | 3,4-Di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands | SCHERING CORPORATION AND PHARMACOPEIA, INC. | 2007-01-25 | — | — | US | disclosed |
| US-20040063780-A1 | Pharmaceutical preparations for treatment of type II diabetes and methods for treatment of type II diabetes | CHUGAI SEIYAKU KABUSHIKI KAISHA | 2004-04-01 | — | — | US | disclosed |