Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 18/20 | 0.70 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | KMO | O15229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17263203 | 0.84 | ACSS2 (0.70) | ACSS2 | |
| SCHEMBL17267026 | 0.82 | ACSS2 (1.00) | ACSS2 | |
| SCHEMBL17263139 | 0.80 | ACSS2 (0.82) | ACSS2 | |
| SCHEMBL17263107 | 0.78 | ACSS2 (0.61) | ACSS2 | |
| SCHEMBL17263191 | 0.77 | ACSS2 (0.69) | ACSS2 | |
| SCHEMBL17263221 | 0.76 | ACSS2 (0.66) | ACSS2 | |
| SCHEMBL17263094 | 0.75 | ACSS2 (0.64) | ACSS2 | |
| SCHEMBL17263186 | 0.73 | ACSS2 (0.61) | ACSS2 | |
| SCHEMBL18674947 | 0.72 | ACSS2 (0.63) | ACSS2 | |
| SCHEMBL24815611 | 0.72 | ACSS2 (0.55) | ACSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015175845-A1 | BENZIMIDAZOLE DERIVATIVES AND USES THEREOF | PELOTON THERAPEUTICS, INC. (US) | 2015-11-19 | — | — | WO | disclosed |