SCHEMBL17263276

SCHEMBL17263276

Cc1cc2c(cc1-c1nccnc1C)C(C)(C)c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 5/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 1/20 0.33
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
ALDH1A1 P00352 1/20 0.30
KCNQ2 O43526 1/20 0.30
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18571628 0.86 PDK2 (0.38) PDK2CYP1A2CYP2C19KMT2AKDM4E
SCHEMBL17263267 0.84 CYP1A2 (0.35) PDK2CYP1A2CYP2C19KMT2AKCNQ2
SCHEMBL14495843 0.82 JAK3 (0.37) PDK2KMT2A
SCHEMBL17263285 0.82 PDK2 (0.34) PDK2
SCHEMBL12320586 0.81 CYP2A6 (0.40) CYP1A2CYP2C19KMT2AKDM4ENPC1
SCHEMBL14495844 0.81 NQO2 (0.33) PDK2KMT2AESR1ESR2MLNR
SCHEMBL17263284 0.79 PDK2 (0.38) PDK2KDM4EALDH1A1
SCHEMBL18571287 0.78 KDM4E (0.44) PDK2CYP1A2KMT2AKDM4ENPC1
SCHEMBL10025114 0.76 PDK2 (0.36) PDK2CYP1A2CYP2C19KMT2AKDM4E
SCHEMBL5062909 0.76 HTR2A (0.43) PDK2KMT2AESR1ESR2KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187689-B2 Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-17 US disclosed