SCHEMBL17263267

SCHEMBL17263267

CCc1nccnc1-c1cc2c(cc1C)-c1ccccc1C2(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
KCNQ2 O43526 1/20 0.30
MLNR O43193 1/20 0.30
NR1I2 O75469 1/20 0.30
CHRM2 P08172 1/20 0.30
ADRB1 P08588 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
CHRM3 P20309 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
HTR2A P28223 1/20 0.30
HTR2C P28335 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11996934 0.88 KMT2A (0.36) CYP1A2CYP2C19KMT2AKCNQ2PDK2
SCHEMBL17263276 0.84 PDK2 (0.33) CYP1A2CYP2C19KMT2AKCNQ2MLNR
SCHEMBL18571628 0.81 PDK2 (0.38) CYP1A2CYP2C19KMT2AADRA1APDK2
SCHEMBL12320586 0.77 CYP2A6 (0.40) CYP1A2CYP2C19KMT2AHTR1AHTR2A
SCHEMBL17263284 0.75 PDK2 (0.38) PDK2
SCHEMBL17263265 0.75 CCR1 (0.37) CYP1A2
SCHEMBL18571287 0.74 KDM4E (0.44) CYP1A2KMT2APDK2
SCHEMBL14495844 0.74 NQO2 (0.33) KMT2AMLNRNR1I2CHRM2ADRB1
SCHEMBL14495843 0.73 JAK3 (0.37) KMT2APDK2
SCHEMBL17263285 0.73 PDK2 (0.34) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9187689-B2 Organometallic complex and light-emitting element, light-emitting device, and electronic device using the same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-11-17 US disclosed