Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 9/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12648807 | 0.93 | SCD (0.68) | SCDKDM4EMAPTL3MBTL1GFER | |
| Hydrochloric Acid SCHEMBL1568728 | 0.92 | SCD (0.67) | SCDKDM4EMAPTL3MBTL1GFER | |
| SCHEMBL1767627 | 0.91 | SCD (0.56) | SCDKDM4EMAPTL3MBTL1GFER | |
| SCHEMBL1767507 | 0.90 | SCD (0.57) | SCDKDM4EMAPTL3MBTL1GFER | |
| SCHEMBL1767547 | 0.88 | SCD (0.54) | SCDKDM4EMAPTL3MBTL1GFER | |
| SCHEMBL17263333 | 0.86 | SCD (0.53) | SCDMAPTL3MBTL1LMNARAB9A | |
| SCHEMBL18121968 | 0.86 | SCD (0.42) | SCDTSHR | |
| SCHEMBL1767557 | 0.86 | SCD (0.58) | SCDKDM4EMAPTL3MBTL1GFER | |
| SCHEMBL1767498 | 0.84 | SCD (0.51) | SCD | |
| SCHEMBL1767542 | 0.83 | SCD (0.49) | SCDKDM4EMAPTL3MBTL1GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187426-B2 | Organic compounds | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |