Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 8/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1767626 | 0.96 | SCD (0.56) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1767544 | 0.93 | L3MBTL1 (0.54) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1568693 | 0.93 | SCD (0.62) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1767388 | 0.93 | L3MBTL1 (0.54) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1767455 | 0.90 | HDAC1 (0.52) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1767520 | 0.90 | SCD (0.50) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1767389 | 0.90 | SCD (0.50) | SCDTP53HDAC1L3MBTL1RAB9A | |
| SCHEMBL1767807 | 0.87 | SCD (0.49) | SCDTP53HDAC1RAB9ASMN1; SMN2 | |
| SCHEMBL1767484 | 0.87 | SCD (0.66) | SCDTP53HDAC1L3MBTL1SMN1; SMN2 | |
| SCHEMBL1767382 | 0.87 | SCD (0.47) | SCDTP53HDAC1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9187426-B2 | Organic compounds | NOVARTIS AG (CH) | 2015-11-17 | — | — | US | disclosed |