Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10585264 | 0.98 | LMNA (0.38) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| SCHEMBL276968 | 0.98 | LMNA (0.38) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| Phosphine SCHEMBL15612730 | 0.95 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| SCHEMBL29077038 | 0.95 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| SCHEMBL4107502 | 0.95 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| Water SCHEMBL8206792 | 0.95 | LMNA (0.36) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| SCHEMBL11572564 | 0.93 | LMNA (0.35) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| Methylamine SCHEMBL28157198 | 0.91 | SMN1; SMN2 (0.35) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| Trimethylammonium SCHEMBL15820208 | 0.89 | SMN1; SMN2 (0.34) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 | |
| Phosphoric Acid SCHEMBL1486023 | 0.89 | SMN1; SMN2 (0.38) | LMNAALDH1A1SMN1; SMN2KDM4EDUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288111-B2 | Immunoassays exhibiting reduced cross-reactivity with hydrophobic drug analyte metabolites | ABBOTT LABORATORIES (US) | 2012-10-16 | — | — | US | disclosed |
| WO-2012013195-A3 | IMPROVEMENTS RELATING TO WIND TURBINES | VESTAS WIND SYSTEMS A/S (DK) | 2012-05-10 | — | — | WO | disclosed |
| EP-2174137-B1 | IMMUNOASSAYS EXHIBITING REDUCED CROSS-REACTIVITY WITH HYDROPHOBIC DRUG ANALYTE METABOLITES | ABBOTT LAB (US) | 2011-11-30 | — | — | EP | disclosed |
| EP-2174137-A1 | IMMUNOASSAYS EXHIBITING REDUCED CROSS-REACTIVITY WITH HYDROPHOBIC DRUG ANALYTE METABOLITES | Abbott Laboratories (US) | 2010-04-14 | — | — | EP | disclosed |
| US-20080311676-A1 | IMMUNOASSAYS EXHIBITING REDUCED CROSS-REACTIVITY WITH HYDROPHOBIC DRUG ANALYTE METABOLITES | ABBOTT LABORATORIES (US) | 2008-12-18 | — | — | US | disclosed |
| WO-2008147982-A1 | IMMUNOASSAYS EXHIBITING REDUCED CROSS-REACTIVITY WITH HYDROPHOBIC DRUG ANALYTE METABOLITES | ABBOTT LABORATORIES (US) | 2008-12-04 | — | — | WO | disclosed |