Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.53 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA1 | P00915 | 5/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8752938 | 0.99 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL31314288 | 0.95 | MALT1 (0.50) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL12143602 | 0.95 | MALT1 (0.50) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL2451977 | 0.90 | MALT1 (0.52) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL29727448 | 0.90 | MALT1 (0.52) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL6298459 | 0.88 | MALT1 (0.49) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL6709260 | 0.86 | MALT1 (0.45) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL25719625 | 0.85 | GAA (0.58) | TPSAB1TPSD1TPSG1CA12CA1 | |
| SCHEMBL9773851 | 0.82 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1TDP1MALT1 | |
| SCHEMBL22291518 | 0.82 | TPSAB1 (0.54) | TPSAB1TPSD1TPSG1TDP1MALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150330992-A1 | RAPID DISCOVERY AND SCREENING OF ENZYME ACTIVITY USING MASS SPECTROMETRY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-11-19 | — | — | US | disclosed |