Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | AGXT | P21549 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2557127 | 0.90 | EPHX1 (0.45) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL3669451 | 0.88 | CHRNB2 (0.44) | IDO1CHRNB2CHRNA4AGXTSLC1A3 | |
| SCHEMBL11197240 | 0.88 | SLC1A3 (0.46) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL24566617 | 0.85 | CHRNB2 (0.41) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL14173592 | 0.83 | SLC1A3 (0.42) | IDO1CHRNB2CHRNA4AGXTSLC1A3 | |
| SCHEMBL22433619 | 0.83 | IDO1 (0.46) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL4299693 | 0.82 | IDO1 (0.50) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL28795432 | 0.80 | SLC1A3 (0.50) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL7864015 | 0.78 | IDO1 (0.46) | IDO1CHRNB2CHRNA4AGXTTSHR | |
| SCHEMBL18579815 | 0.78 | IDO1 (0.46) | IDO1CHRNB2CHRNA4AGXTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9468706-B2 | Phosphoryl choline coating compositions | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-9468706-B2 | Phosphoryl choline coating compositions | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150328375-A1 | Phosphoryl Choline Coating Compositions | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-11-19 | — | — | US | disclosed |
| US-20150328375-A1 | Phosphoryl Choline Coating Compositions | ABBOTT CARDIOVASCULAR SYSTEMS (US) | 2015-11-19 | — | — | US | disclosed |