SCHEMBL1726499

SCHEMBL1726499

CCCCO[PH](=O)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 2/20 0.44
TSHR P16473 5/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
ALDH1A1 P00352 5/20 0.38
CYP3A4 P08684 2/20 0.38
MAPK1 P28482 2/20 0.38
HPGD P15428 1/20 0.37
HIF1A Q16665 1/20 0.37
TP53 P04637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
LMNA P02545 1/20 0.36
KDM4E B2RXH2 1/20 0.36
MEN1 O00255 1/20 0.36
RECQL P46063 1/20 0.36
KMT2A Q03164 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27492981 0.94 LTA4H (0.44) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL27657692 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL27532661 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL27657814 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL9810579 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL29241732 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL27509699 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL3817411 0.93 TSHR (0.45) LTA4HTSHRALDH1A1CYP3A4MAPK1
Ammonia Solution, Strong SCHEMBL9441912 0.91 TSHR (0.44) LTA4HTSHRALDH1A1CYP3A4MAPK1
SCHEMBL752002 0.88 KMT2A (0.41) LTA4HTSHRTDP1L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114478624-B Telomer of diethyl aluminum phosphinate and preparation method thereof 兰州瑞朴科技有限公司 2024-07-02 CN claimed
CN-114181250-A Alkenyl phosphine compound and preparation method thereof 中国石油化工股份有限公司 2022-03-15 CN claimed
CN-109293805-B Olefin polymerization solid catalytic component, component preparation method and catalyst system thereof 中国石油天然气股份有限公司 2021-03-09 CN claimed
CN-112119116-A Non-halogen flame-retardant resin composition and flame-retardant resin molded article made therefrom 株式会社LG化学 2020-12-22 CN claimed
CN-111808133-A Aluminum diethyl phosphinate material and preparation method thereof 浙江新化化工股份有限公司 2020-10-23 CN claimed
US-8633127-B2 Selective hydrogenation catalyst and methods of making and using same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2014-01-21 US claimed
EP-0826690-B1 Process for the preparation of 2-cyanoethyl-phosphinic acid esters TICONA GMBH (DE) 2001-11-14 EP claimed
EP-0029169-B1 POLYMERS AND PROCESS FOR THEIR PREPARATION Agfa-Gevaert AG (DE) 1983-05-18 EP claimed
US-4329441-A PHOSPHORUS COMPOUND CATALYST AGFA-GEVAERT AG AKTIENGESELLSCHAFT (DE) 1982-05-11 US claimed
EP-0029169-A2 Polymers and process for their preparation Agfa-Gevaert AG (DE) 1981-05-27 EP claimed
CN-114478624-B Telomer of diethyl aluminum phosphinate and preparation method thereof 兰州瑞朴科技有限公司 2024-07-02 CN disclosed
CN-115109310-B Flame retardant and corresponding flame-retardant plastic product 兰州瑞朴科技有限公司 2024-07-02 CN disclosed
US-20230406981-A1 POLYMER, FLAME-RETARDANT COMPOSITION, AND METHOD OF PRODUCING POLYMER KURARAY CO., LTD. (JP) 2023-12-21 US disclosed
US-20230407076-A1 POLYMER, FLAME-RETARDANT COMPOSITION, AND METHOD FOR PRODUCING POLYMER KURARAY CO., LTD. (JP) 2023-12-21 US disclosed
EP-3412726-B1 NON-HALOGEN FLAME-RETARDANT RESIN COMPOSITION LG CHEMICAL LTD (KR) 2023-12-06 EP disclosed
US-7534809-B2 Phospho-indoles as HIV inhibitors IDENIX PHARMACEUTICALS, INC. (US) 2009-05-19 US disclosed
EP-1799696-B1 PHOSPHOINDOLES AS HIV INHIBITORS IDENIX PHARMACEUTICALS INC (US) 2008-11-12 EP disclosed
EP-1961757-A1 Phosphoindoles as HIV inhibitors IDENIX Pharmaceuticals, Inc. (US) 2008-08-27 EP disclosed
EP-0029169-B1 POLYMERS AND PROCESS FOR THEIR PREPARATION Agfa-Gevaert AG (DE) 1983-05-18 EP disclosed
US-4052486-A PROCESS FOR PREPARING CYCLIC PHOSPHINIC ACID ESTERS HOECHST AKTIENGESELLSCHAFT (DT) 1977-10-04 US disclosed