SCHEMBL17265015

SCHEMBL17265015

Oc1cc(F)ccc1-c1nc2ccccc2s1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.72
KDM4E B2RXH2 8/20 0.72
RAB9A P51151 7/20 0.72
NPC1 O15118 5/20 0.72
NPSR1 Q6W5P4 2/20 0.72
CASP6 P55212 1/20 0.60
SMN1; SMN2 Q16637 5/20 0.58
MEN1 O00255 5/20 0.58
KMT2A Q03164 5/20 0.58
GAA P10253 4/20 0.58
TDP1 Q9NUW8 2/20 0.58
L3MBTL1 Q9Y468 2/20 0.58
POLB P06746 2/20 0.58
HSD17B10 Q99714 2/20 0.58
APP P05067 1/20 0.58
THRB P10828 1/20 0.58
ALOX15 P16050 1/20 0.58
CASP1 P29466 1/20 0.58
SNCA P37840 1/20 0.58
CASP7 P55210 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2791070 0.89 MAPT (0.69) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL7192101 0.84 KDM4E (1.00) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL29693710 0.84 KDM4E (1.00) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL8374081 0.83 KDM4E (0.76) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL1549967 0.83 KDM4E (0.76) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL31120341 0.83 MAPT (0.57) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL13806278 0.83 NPC1 (0.67) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL4278803 0.83 NPC1 (0.67) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL13806264 0.83 APP (0.68) MAPTKDM4ERAB9ANPC1NPSR1
SCHEMBL30714873 0.83 KDM4E (0.74) MAPTKDM4ERAB9ANPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9601704-B2 Organic light-emitting device and display apparatus CANON KABUSHIKI KAISHA (JP) 2017-03-21 US disclosed
US-9466804-B2 Organic light-emitting element CANON KABUSHIKI KAISHA (JP) 2016-10-11 US disclosed
US-20150364703-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS CANON KABUSHIKI KAISHA (JP) 2015-12-17 US disclosed
US-20150357587-A1 ORGANIC LIGHT-EMITTING ELEMENT SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-12-10 US disclosed
US-20150333279-A1 ORGANIC LIGHT-EMITTING ELEMENT AND DISPLAY APPARATUS SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-11-19 US disclosed