SCHEMBL30714873

SCHEMBL30714873

Oc1cc(-c2nc3ccccc3s2)ccc1-c1nc2ccccc2s1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 10/20 0.74
MAPT P10636 8/20 0.74
RAB9A P51151 8/20 0.74
NPC1 O15118 8/20 0.74
NPSR1 Q6W5P4 2/20 0.74
SMN1; SMN2 Q16637 6/20 0.68
ALDH1A1 P00352 5/20 0.68
HSD17B10 Q99714 4/20 0.68
KMT2A Q03164 4/20 0.68
TP53 P04637 3/20 0.68
HPGD P15428 3/20 0.68
MEN1 O00255 3/20 0.68
HCRTR1 O43613 1/20 0.68
MAPK1 P28482 1/20 0.68
BLM P54132 1/20 0.68
GAA P10253 3/20 0.66
GLA P06280 3/20 0.66
LMNA P02545 3/20 0.66
NFKB1 P19838 3/20 0.65
NFKB2 Q00653 3/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9293186 1.00 KDM4E (0.74) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL2788048 0.91 KDM4E (0.70) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL25288484 0.89 KDM4E (0.71) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL12470903 0.89 KDM4E (0.69) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL30466258 0.89 KDM4E (0.69) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL29693710 0.85 KDM4E (1.00) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL7192101 0.85 KDM4E (1.00) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL30714885 0.85 KDM4E (0.59) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL1549967 0.85 KDM4E (0.76) KDM4EMAPTRAB9ANPC1NPSR1
SCHEMBL8374081 0.85 KDM4E (0.76) KDM4EMAPTRAB9ANPC1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023242454-A1 HYBRID MATERIAL FOR DETECTING ACID AND BASE VAPOURS UNIVERSIDAD DE CASTILLA LA MANCHA (ES) 2023-12-21 WO disclosed