SCHEMBL17265653

SCHEMBL17265653

CCc1cc(N)ccc1N1CCN(c2ccc(N)cc2CC)CC1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.54
GAA P10253 6/20 0.54
GFER P55789 4/20 0.54
RAD52 P43351 3/20 0.54
KDM4E B2RXH2 3/20 0.50
ALDH1A1 P00352 6/20 0.49
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
THRB P10828 2/20 0.49
NR4A1 P22736 1/20 0.49
PTK2B Q14289 1/20 0.49
POLB P06746 2/20 0.46
SMN1; SMN2 Q16637 3/20 0.45
TDP1 Q9NUW8 2/20 0.45
HTT P42858 2/20 0.45
HSD17B10 Q99714 2/20 0.45
ALOX15 P16050 1/20 0.45
YWHAG P61981 1/20 0.45
MAPK1 P28482 2/20 0.44
LMNA P02545 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30879098 0.93 MAPT (0.61) MAPTGAAGFERRAD52KDM4E
SCHEMBL12006141 0.93 MAPT (0.61) MAPTGAAGFERRAD52KDM4E
SCHEMBL15509139 0.93 MAPT (0.59) MAPTGAAGFERRAD52KDM4E
SCHEMBL18807131 0.92 MAPT (0.68) MAPTGAAGFERRAD52KDM4E
SCHEMBL22174764 0.89 MAPT (0.46) MAPTGAAGFERRAD52KDM4E
SCHEMBL24630249 0.88 MAPT (0.61) MAPTGAAGFERRAD52KDM4E
SCHEMBL17264121 0.88 ALDH1A1 (0.50) MAPTGAAGFERRAD52KDM4E
SCHEMBL29769230 0.88 MAPT (0.61) MAPTGAAGFERRAD52KDM4E
SCHEMBL26640483 0.85 ALDH1A1 (0.48) MAPTGAAGFERRAD52KDM4E
SCHEMBL17265651 0.85 MAPT (0.51) MAPTGAAGFERRAD52KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed
US-20150329781-A1 LIQUID CRYSTAL ALIGNMENT AGENT, LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY ELEMENT CHI MEI CORPORATION (TW) 2015-11-19 US disclosed