⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1728125 | 0.72 | — | — | |
| Hydrogen Sulfide SCHEMBL21878631 | 0.68 | — | — | |
| SCHEMBL1557622 | 0.67 | — | — | |
| SCHEMBL10776420 | 0.67 | — | — | |
| SCHEMBL8100712 | 0.67 | — | — | |
| SCHEMBL737387 | 0.67 | — | — | |
| SCHEMBL1470335 | 0.67 | — | — | |
| SCHEMBL1470276 | 0.67 | FAAH (0.47) | — | |
| SCHEMBL2903929 | 0.67 | — | — | |
| SCHEMBL387112 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115093418-A | [1,2,3] triazolo [4,5-d ] pyrimidine derivatives having affinity for cannabinoid type 2 receptors | 豪夫迈·罗氏有限公司 | 2022-09-23 | — | — | CN | claimed |
| CN-115073476-A | [1,2,3] triazolo [4,5-d ] pyrimidine derivatives having affinity for cannabinoid type 2 receptors | 豪夫迈·罗氏有限公司 | 2022-09-20 | — | — | CN | claimed |
| US-10457685-B2 | [1,2,3]triazolo[4,5-D]pyrimidine derivatives with affinity for the type-2 cannabinoid receptor | HOFFMANN-LA ROCHE INC. (US) | 2019-10-29 | — | — | US | claimed |
| US-20190127384-A1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | HOFFMANN-LA ROCHE INC. (US) | 2019-05-02 | — | — | US | claimed |
| EP-3475282-A1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | H. Hoffnabb-La Roche Ag (CH) | 2019-05-01 | — | — | EP | claimed |
| CN-109348716-A | [1,2,3] triazolo [4,5-d ] pyrimidine derivatives having affinity for cannabinoid type 2 receptors | 豪夫迈·罗氏有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-108666620-A | A kind of nonaqueous electrolytic solution of high-voltage lithium ion batteries | 珠海市赛纬电子材料股份有限公司 | 2018-10-16 | — | — | CN | claimed |
| WO-2017220517-A1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | F. HOFFMANN-LA ROCHE AG (CH) | 2017-12-28 | — | — | WO | claimed |
| CN-107382742-A | A kind of new synthetic method of fluorine 4 (trifluoromethyl) anilinechloride of 5 chlorine of fragrance intermediate containing trifluoromethyl 2 | 梁江丽 | 2017-11-24 | — | — | CN | claimed |
| WO-2006060654-A2 | PESTICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2006-06-08 | — | — | WO | claimed |
| US-20050203067-A1 | Pesticidal compositions and methods | DIVERGENCE, INC. | 2005-09-15 | — | — | US | claimed |
| EP-4295841-A2 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | The Scripps Research Institute (US) | 2023-12-27 | — | — | EP | disclosed |
| EP-3892610-B1 | SULFUR (VI) FLUORIDE COMPOUNDS AND THEIR USE IN CLICK-REACTION | SCRIPPS RESEARCH INST (US) | 2023-08-16 | — | — | EP | disclosed |
| EP-3475282-B1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | HOFFMANN LA ROCHE (CH) | 2023-08-09 | — | — | EP | disclosed |
| EP-4108665-A1 | [1,2,3]TRIAZOLO[4,5-D]PYRIMIDINE DERIVATIVES WITH AFFINITY FOR THE TYPE-2 CANNABINOID RECEPTOR | F. Hoffmann-La Roche AG (CH) | 2022-12-28 | — | — | EP | disclosed |
| EP-2006289-A1 | PYRAZOLE-TYPE CYANINE DYE | Wako Pure Chemical Industries, Ltd. (JP) | 2008-12-24 | — | — | EP | disclosed |
| WO-2006060654-A2 | PESTICIDAL COMPOSITIONS AND METHODS | DIVERGENCE, INC. (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050203067-A1 | Pesticidal compositions and methods | DIVERGENCE, INC. | 2005-09-15 | — | — | US | disclosed |
| EP-0740690-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995020014-A1 | MONOAZO DYES CONTAINING A FLUOROSULPHONYL GROUP AND USE THEREOF | ZENECA LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |