Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 12/20 | 1.00 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.82 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.82 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.82 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.82 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.82 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.82 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | MTOR | P42345 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17267513 | 1.00 | SLC7A5 (1.00) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| SCHEMBL17267476 | 1.00 | SLC7A5 (1.00) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| SCHEMBL17267515 | 0.99 | SLC7A5 (1.00) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Fumaric Acid SCHEMBL17267487 | 0.91 | SLC7A5 (0.82) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Fumaric Acid SCHEMBL17267537 | 0.91 | SLC7A5 (0.82) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Fumaric Acid SCHEMBL17267490 | 0.91 | SLC7A5 (0.82) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Fumaric Acid SCHEMBL17267580 | 0.91 | SLC7A5 (0.82) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Fumaric Acid SCHEMBL17267491 | 0.91 | SLC7A5 (0.82) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Fumaric Acid SCHEMBL17267583 | 0.91 | SLC7A5 (0.82) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 | |
| Norfluoxetine SCHEMBL3750512 | 0.90 | SLC6A4 (1.00) | SLC7A5SLC6A4SLC6A2SLC6A3KCNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2947066-B1 | PHENOXYALKYLAMINE COMPOUND | UNIV OSAKA (JP) | 2018-09-19 | — | — | EP | disclosed |
| US-9771316-B2 | Phenoxyalkylamine compound | OSAKA UNIVERSITY (JP) | 2017-09-26 | — | — | US | disclosed |
| US-9771316-B2 | Phenoxyalkylamine compound | OSAKA UNIVERSITY (JP) | 2017-09-26 | — | — | US | disclosed |
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | KNC LABORATORIES CO., LTD. (JP) | 2015-11-26 | — | — | US | disclosed |
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | KNC LABORATORIES CO., LTD. (JP) | 2015-11-26 | — | — | US | disclosed |
| EP-2947066-A1 | PHENOXYALKYLAMINE COMPOUND | Osaka University (JP) | 2015-11-25 | — | — | EP | disclosed |
| EP-2947066-A1 | PHENOXYALKYLAMINE COMPOUND | Osaka University (JP) | 2015-11-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150336876-A1 | PHENOXYALKYLAMINE COMPOUND | LATS1, LATS2, SHC1 | SLC7A5 63/4885SLC6A4 413/4885SLC6A2 240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.