Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19068174 | 1.00 | SLC6A4 (0.38) | SLC6A4TDP1LMNACNR1ADRA1A | |
| SCHEMBL5932192 | 0.88 | LMNA (0.38) | SLC6A4TDP1LMNACNR1ADRA1A | |
| SCHEMBL13995992 | 0.85 | TDP1 (0.44) | TDP1LMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL104880 | 0.82 | — | — | |
| SCHEMBL25095029 | 0.81 | SLC6A4 (0.37) | SLC6A4TDP1 | |
| SCHEMBL13995972 | 0.81 | LMNA (0.33) | TDP1LMNACNR1ADRA1AKDM4E | |
| SCHEMBL19116400 | 0.80 | SLC6A4 (0.32) | SLC6A4 | |
| Hydrochloric Acid SCHEMBL22575324 | 0.79 | TDP1 (0.44) | SLC6A4TDP1LMNACNR1ADRA1A | |
| SCHEMBL21277057 | 0.79 | SLC6A4 (0.36) | SLC6A4TDP1 | |
| SCHEMBL7933710 | 0.79 | LMNA (0.32) | TDP1LMNACNR1ADRA1AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255738-B1 | GONADOTROPIN-RELEASING HORMONE RECEPTOR ANTAGONISTS AND METHODS RELATING THERETO | NEUROCRINE BIOSCIENCES INC (US) | 2012-03-07 | — | — | EP | disclosed |