Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 17/20 | 0.56 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | PDE6D | O43924 | 1/20 | 0.33 |
| ▸ | PDE6A | P16499 | 1/20 | 0.33 |
| ▸ | PDE6G | P18545 | 1/20 | 0.33 |
| ▸ | PDE6B | P35913 | 1/20 | 0.33 |
| ▸ | PDE6C | P51160 | 1/20 | 0.33 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3099526 | 0.97 | PTGES (0.58) | PTGESP2RY12 | |
| SCHEMBL11962197 | 0.90 | PTGES (0.49) | PTGESP2RY12 | |
| SCHEMBL3101702 | 0.85 | PTGES (0.73) | PTGES | |
| SCHEMBL3100739 | 0.84 | PTGES (0.79) | PTGES | |
| SCHEMBL3099096 | 0.83 | PTGES (0.58) | PTGES | |
| SCHEMBL11961902 | 0.80 | PTGES (0.63) | PTGES | |
| SCHEMBL15379477 | 0.76 | PTGES (0.61) | PTGES | |
| SCHEMBL9939820 | 0.74 | PTGES (0.44) | PTGES | |
| SCHEMBL9939985 | 0.74 | PTGES (0.45) | PTGES | |
| SCHEMBL3106287 | 0.74 | PTGES (0.47) | PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403852-A1 | 3H-IMIDAZO [4, 5 -C]PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS | Boehringer Ingelheim International GmbH (DE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100249-A1 | 3H-IMIDAZO [4, 5 -C] PYRIDINE- 6 -CARBOXAMIDES AS ANTI- INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-10 | — | — | WO | disclosed |