SCHEMBL1727115

SCHEMBL1727115

Cc1ccc(P(C)(=O)c2ccc(C)cc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 1.00
LMNA P02545 4/20 0.59
TSHR P16473 2/20 0.59
GAA P10253 4/20 0.52
ESR1 P03372 1/20 0.52
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 2/20 0.47
ACHE P22303 1/20 0.47
CYP3A4 P08684 1/20 0.44
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
MMP8 P22894 1/20 0.41
NPC1 O15118 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 2/20 0.39
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5159485 0.92 HPGD (0.85) HPGDLMNATSHRGAAESR1
Toluene SCHEMBL27848238 0.83 HPGD (0.71) HPGDLMNATSHRGAAESR1
SCHEMBL3888438 0.82 HPGD (0.70) HPGDLMNATSHRGAAMEN1
SCHEMBL13321945 0.79 HPGD (0.63) HPGDLMNATSHRMEN1KMT2A
SCHEMBL262688 0.79 HPGD (0.65) HPGDLMNATSHRGAAMEN1
SCHEMBL5435185 0.79 HPGD (0.65) HPGDLMNATSHRGAAMEN1
SCHEMBL10703445 0.78 HPGD (0.64) HPGDLMNATSHRGAAMEN1
SCHEMBL27614826 0.78 LMNA (0.68) HPGDLMNATSHRGAAESR1
SCHEMBL6626629 0.77 HPGD (0.62) HPGDLMNATSHRGAAMEN1
SCHEMBL28653912 0.77 HPGD (0.62) HPGDLMNATSHRGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2403642-B1 METHODS OF USING A SELECTIVE HYDROGENATION CATALYST CHEVRON PHILLIPS CHEMICAL CO LP (US) 2017-08-02 EP claimed
CN-115651017-B Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative 中南大学 2025-05-27 CN disclosed
US-11780861-B2 Phosphine reagents for azine fluoroalkylation COLORADO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2023-10-10 US disclosed
CN-115651017-A Method for selectively preparing benzyl or alkyl phosphine oxide compound based on benzyl thioether derivative 中南大学 2023-01-31 CN disclosed
EP-3144064-B1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL CO LP (US) 2021-07-28 EP disclosed
EP-3377596-A1 SELECTIVE HYDROGENATION USING A FLOW INDEX Chevron Phillips Chemical Company LP (US) 2018-09-26 EP disclosed
US-20180148260-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2018-05-31 US disclosed
US-9914676-B2 Selective hydrogenation using a flow index CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2018-03-13 US disclosed
US-20170349507-A1 Selective Hydrogenation Using a Flow Index CHEVRON PHILLIPS CHEMICAL COMPANY LP 2017-12-07 US disclosed
EP-3218104-A1 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2017-09-20 EP disclosed
US-8173276-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2012-05-08 US disclosed
EP-2403642-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME Chevron Phillips Chemical Company LP (US) 2012-01-11 EP disclosed
WO-2010101736-A2 SELECTIVE HYDROGENATION CATALYST AND METHODS OF MAKING AND USING SAME CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-09-10 WO disclosed
US-20100228065-A1 Selective Hydrogenation Catalyst and Methods of Making and Using Same CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-09-09 US disclosed
US-20100102305-A1 MATERIALS FOR ELECTROLUMINESCENCE AND THE UTILIZATION THEREOF MERCK PATENT GMBH (DE) 2010-04-29 US disclosed
US-7659540-B2 Materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2010-02-09 US disclosed
US-20070080343-A1 New materials for electroluminescence and the utilization thereof MERCK PATENT GMBH (DE) 2007-04-12 US disclosed
US-4675446-A OXIDATION OF PHOSPHINE SULFIDES HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-23 US disclosed
US-4101655-A Insecticidal and ovicidal method M & T CHEMICALS INC. (US) 1978-07-18 US disclosed
US-3989824-A MITICIDES M & T CHEMICALS INC. (US) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11780861-B2 Phosphine reagents for azine fluoroalkylation PTPN3, PHOSPHO1, SKIC3 HPGD 4863/4885LMNA 3787/4885TSHR 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.