Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Lithium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL17272203 | 0.98 | CA2 (0.39) | CA2HTTLMNAMEN1TSHR | |
| SCHEMBL17272282 | 0.97 | CA2 (0.38) | CA2HTTLMNAMEN1TSHR | |
| Lithium Ion SCHEMBL17272156 | 0.92 | CA2 (0.36) | CA2HTTLMNAMEN1TSHR | |
| Potassium Ion SCHEMBL17272197 | 0.90 | CA2 (0.37) | CA2HTTLMNAMEN1TSHR | |
| Lithium Ion SCHEMBL17272445 | 0.89 | CA2 (0.35) | CA2HTTLMNA | |
| SCHEMBL17272180 | 0.89 | CA2 (0.36) | CA2HTTLMNAMEN1TSHR | |
| Potassium Ion SCHEMBL17272229 | 0.87 | CA2 (0.36) | CA2HTTLMNAMEN1TSHR | |
| Potassium Ion SCHEMBL29780202 | 0.87 | CA2 (0.36) | CA2HTTLMNAMEN1TSHR | |
| SCHEMBL17272018 | 0.86 | CA2 (0.35) | CA2HTTLMNA | |
| SCHEMBL29780214 | 0.86 | CA2 (0.35) | CA2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9718905-B2 | Polythiophene, water-soluble electrically conductive polymer using it, and method for producing it | TOSOH CORPORATION (JP) | 2017-08-01 | — | — | US | disclosed |
| US-20150337061-A1 | POLYTHIOPHENE, WATER-SOLUBLE ELECTRICALLY CONDUCTIVE POLYMER USING IT, AND METHOD FOR PRODUCING IT | TOSOH CORPORATION (JP) | 2015-11-26 | — | — | US | disclosed |