SCHEMBL17273145

SCHEMBL17273145

CCC(CC)(c1ccc(O)c(OC)c1)c1ccc(O)c(OC)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 7/20 0.60
ESR2 Q92731 5/20 0.60
AR P10275 2/20 0.60
MAOB P27338 1/20 0.53
TAAR1 Q96RJ0 2/20 0.49
TSHR P16473 1/20 0.49
MAPK1 P28482 1/20 0.49
HSD17B2 P37059 2/20 0.47
GAA P10253 1/20 0.47
FOS P01100 1/20 0.47
TTR P02766 1/20 0.47
JUN P05412 1/20 0.47
NR3C1 P04150 1/20 0.47
HSD17B1 P14061 1/20 0.47
LMNA P02545 1/20 0.47
GLA P06280 1/20 0.47
SLC22A6 Q4U2R8 1/20 0.47
SLC22A8 Q8TCC7 1/20 0.47
MEN1 O00255 1/20 0.47
RAB9A P51151 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17281707 0.89 ESR1 (0.58) ESR1ESR2ARMAOBTAAR1
SCHEMBL3436061 0.85 MAOB (0.50) MAOBTAAR1TSHRMAPK1HSD17B2
SCHEMBL1525445 0.85 MAOB (0.50) ARMAOBTAAR1TSHRMAPK1
SCHEMBL19431278 0.85 MAOB (0.50) MAOBTAAR1TSHRMAPK1HSD17B2
SCHEMBL16649199 0.85 MAOB (0.50) MAOBTAAR1TSHRMAPK1HSD17B2
SCHEMBL11648169 0.84 TSHR (0.49) MAOBTAAR1TSHRMAPK1HSD17B2
SCHEMBL29105737 0.83 ESR1 (0.48) ESR1ESR2ARMAOB
SCHEMBL28892093 0.82 TAAR1 (0.47) MAOBTAAR1TSHRMAPK1HSD17B2
SCHEMBL125447 0.80 MAOB (0.57) ESR1MAOBTAAR1TSHRMAPK1
SCHEMBL11231259 0.80 ESR1 (0.57) ESR1ESR2ARGAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160299157-A1 METHODS FOR DETERMINING RELATIVE BINDING ENERGY OF MONOMERS AND METHODS OF USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-10-13 US disclosed
US-20160299157-A1 METHODS FOR DETERMINING RELATIVE BINDING ENERGY OF MONOMERS AND METHODS OF USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-10-13 US disclosed
US-20150338423-A1 METHODS FOR DETERMINING RELATIVE BINDING ENERGY OF MONOMERS AND METHODS OF USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed
US-20150338423-A1 METHODS FOR DETERMINING RELATIVE BINDING ENERGY OF MONOMERS AND METHODS OF USING THE SAME SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-11-26 US disclosed