SCHEMBL3436061

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20942165	0.86	CNR2 (0.52)	MAOBTAAR1TSHRMAPK1HSD17B2
	SCHEMBL19431278	0.86	MAOB (0.50)	MAOBTAAR1TSHRMAPK1HSD17B2
	SCHEMBL3662594	0.86	CNR1 (0.50)	TSHRMAPK1GAACNR1CNR2
	SCHEMBL16649199	0.86	MAOB (0.50)	MAOBTAAR1TSHRMAPK1HSD17B2
	SCHEMBL17273145	0.85	ESR1 (0.60)	MAOBTAAR1TSHRMAPK1HSD17B2
	SCHEMBL27800149	0.84	TSHR (0.53)	MAOBTAAR1TSHRMAPK1HSD17B2
	SCHEMBL13385187	0.83	CNR1 (0.47)	MAPK1CNR1CNR2LMNAMEN1
	SCHEMBL23640626	0.82	MCL1 (0.41)	GAACNR1CNR2GLAMEN1
	SCHEMBL1525445	0.82	MAOB (0.50)	MAOBTAAR1TSHRMAPK1HSD17B2
	SCHEMBL22566844	0.81	MAOB (0.55)	MAOBTAAR1TSHRMAPK1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.