Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | TYMP | P19971 | 1/20 | 0.58 |
| ▸ | TK1 | P04183 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077816 | 1.00 | POLB (0.58) | POLBTYMPTK1BCHE | |
| SCHEMBL1727537 | 1.00 | POLB (0.58) | POLBTYMPTK1BCHE | |
| SCHEMBL5053953 | 1.00 | POLB (0.58) | POLBTYMPTK1BCHE | |
| SCHEMBL6334503 | 1.00 | POLB (0.58) | POLBTYMPTK1BCHE | |
| SCHEMBL10446716 | 1.00 | POLB (0.58) | POLBTYMPTK1BCHE | |
| SCHEMBL22984023 | 0.94 | TYMS (0.56) | POLBTYMPTK1 | |
| SCHEMBL23517951 | 0.94 | TYMS (0.56) | POLBTYMPTK1 | |
| SCHEMBL2460807 | 0.94 | TYMS (0.56) | POLBTYMPTK1 | |
| SCHEMBL22983972 | 0.94 | TYMS (0.56) | POLBTYMPTK1 | |
| SCHEMBL1775528 | 0.94 | TYMS (0.56) | POLBTYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100227-A1 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2012-04-26 | — | — | US | claimed |
| EP-2403494-A2 | KINASE PROTEIN BINDING INHIBITORS | University of Florida Research Foundation, Inc. (US) | 2012-01-11 | — | — | EP | claimed |
| WO-2010102095-A2 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-10 | — | — | WO | claimed |
| US-20120100227-A1 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION (US) | 2012-04-26 | — | — | US | disclosed |
| EP-2403494-A2 | KINASE PROTEIN BINDING INHIBITORS | University of Florida Research Foundation, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010102095-A2 | KINASE PROTEIN BINDING INHIBITORS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-10 | — | — | WO | disclosed |