Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | TYMP | P19971 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460809 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL9015743 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL1775528 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL14064188 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL22983972 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL2460807 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL22983968 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL23517951 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL7535874 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 | |
| SCHEMBL6250998 | 1.00 | TYMS (0.56) | TYMSPOLBTYMPTK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230159922-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | US | disclosed |
| EP-4013428-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | Ionis Pharmaceuticals, Inc. (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2021030763-A1 | MODIFIED OLIGOMERIC COMPOUNDS AND USES THEREOF | IONIS PHARMACEUTICALS, INC. (US) | 2021-02-18 | — | — | WO | disclosed |