Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 6/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 6/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 5/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 5/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16196450 | 0.82 | TSHR (0.43) | TSHRALDH1A1TDP1HDAC4HDAC2 | |
| SCHEMBL29372814 | 0.76 | TSHR (0.56) | TSHRALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL505600 | 0.76 | TSHR (0.56) | TSHRALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL27676988 | 0.73 | ALDH1A1 (0.72) | TSHRALDH1A1TDP1HDAC4HDAC2 | |
| SCHEMBL5831906 | 0.72 | TSHR (0.52) | TSHRALDH1A1TDP1GABRA1GABRB2 | |
| SCHEMBL28837033 | 0.72 | GRIN1 (0.46) | GRIN1GRIN2AGRIN2DGRIN2CGRIN2B | |
| SCHEMBL2695318 | 0.72 | TSHR (0.52) | TSHRALDH1A1TDP1HDAC4HDAC2 | |
| SCHEMBL5994442 | 0.72 | TSHR (0.52) | TSHRALDH1A1TDP1HDAC4HDAC2 | |
| SCHEMBL1160386 | 0.69 | ESR1 (0.47) | TSHRALDH1A1TDP1HPGDHSD17B10 | |
| SCHEMBL1554734 | 0.69 | TSHR (0.31) | TSHRALDH1A1TDP1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3145996-A1 | POLYMERS WITH MODIFIED SURFACE PROPERTIES AND METHOD OF MAKING THE SAME | Invista Technologies S.à r.l. (CH) | 2017-03-29 | — | — | EP | disclosed |
| WO-2015179616-A1 | POLYMERS WITH MODIFIED SURFACE PROPERTIES AND METHOD OF MAKING THE SAME | INVISTA NORTH AMERICA S.A.R.L. (US) | 2015-11-26 | — | — | WO | disclosed |