SCHEMBL17278

SCHEMBL17278

O=[N+]([O-])c1ccccc1S(=O)(=O)Cl

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.70
MEN1 O00255 3/20 0.70
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
MMP1 P03956 1/20 0.59
MMP2 P08253 1/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
MMP13 P45452 1/20 0.59
F2 P00734 3/20 0.54
PRSS1 P07477 3/20 0.54
PRSS2 P07478 3/20 0.54
PRSS3 P35030 3/20 0.54
ALDH1A1 P00352 2/20 0.53
THRB P10828 1/20 0.50
CYP19A1 P11511 1/20 0.49
PKM P14618 1/20 0.49
POLB P06746 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
ACHE P22303 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29425558 1.00 KMT2A (0.70) KMT2AMEN1CA1CA2MMP1
Methane SCHEMBL9273303 0.98 KMT2A (0.68) KMT2AMEN1CA1CA2MMP1
Hydrochloric Acid SCHEMBL7006367 0.98 KMT2A (0.68) KMT2AMEN1CA1CA2MMP1
Hydroxyamine SCHEMBL28312301 0.94 KMT2A (0.63) KMT2AMEN1CA1CA2MMP1
SCHEMBL8712644 0.91 KMT2A (0.67) KMT2AMEN1CA1CA2MMP1
Nitrobenzene SCHEMBL29117067 0.91 KMT2A (0.59) KMT2AMEN1CA1CA2MMP1
SCHEMBL11598452 0.88 KMT2A (0.56) KMT2AMEN1CA1CA2MMP1
SCHEMBL8667209 0.87 KMT2A (0.54) KMT2AMEN1CA1CA2MMP1
SCHEMBL6895483 0.85 KMT2A (0.53) KMT2AMEN1CA1CA2MMP1
SCHEMBL176933 0.85 KMT2A (0.56) KMT2AMEN1CA1CA2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6316 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120081740-A Synthesis method of 2, 6-naphthalene dicarboxylic acid diester 东华大学 2025-06-03 CN claimed
CN-120058715-A Intermediate of RHYNCHINES A compound and synthesis method thereof 河北科技大学 2025-05-30 CN claimed
US-12258343-B2 Method for preparing 2-[(3R)-3-methylmorpholin-4-yl]-4-[1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridine BAYER AKTIENGESELLSCHAFT (DE) 2025-03-25 US claimed
CN-119684260-A Ferritin ligand, ferritin degradation agent, pharmaceutical preparation and application 贵州大学 2025-03-25 CN claimed
CN-119591939-A Crystalline polyaryletherketone surface grafted carbon fiber and preparation method thereof 吉林大学 2025-03-11 CN claimed
CN-119570113-A Crystalline polyaryletherketone surface grafted graphene and preparation method thereof 吉林大学 2025-03-07 CN claimed
CN-119490439-A Preparation method of arylsulfonyl amino quaternary ammonium salt antibacterial agent 苏州华道生物药业股份有限公司 2025-02-21 CN claimed
CN-119425423-A Positively charged composite membrane and preparation method and application thereof 中国石油化工股份有限公司 2025-02-14 CN claimed
CN-118878536-B Pyrrolo [4,3,2-de ] quinoline derivative 齐鲁师范学院 2025-01-03 CN claimed
CN-119219483-A Preparation method of fluororalrana intermediate 重庆普佑生物医药有限公司 2024-12-31 CN claimed
US-5811571-A HALOGENATING AN AROMATIC OR HETEROAROMATIC METHYL SULFIDE OR METHYL SULFOXIDE IN PRESENCE OF WATER SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1998-09-22 US claimed
EP-0576229-B1 Low temperature process for preparing alpha-anomer enriched 2-deoxy-2, 2-difluoro-D-ribofuranosyl sulfonates LILLY CO ELI (US) 1997-12-17 EP claimed
CN-1150796-A Process for preparation of aromatic or heteroaromatic sulfonyl halides SUMITOMO SEIKA CHEMICALS (JP) 1997-05-28 CN claimed
EP-0770599-A1 PROCESS FOR THE PREPARATION OF AROMATIC OR HETEROAROMATIC SULFONYL HALIDES SUMITOMO SEIKA CHEMICALS CO., LTD. (JP) 1997-05-02 EP claimed
US-5401861-A CONTACTING A LACTOL WITH AN AMINE BASE, COOLING AND ADDING A SULFONATING REAGENT ELI LILLY AND COMPANY (US) 1995-03-28 US claimed
EP-0576228-A1 Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-12-29 EP claimed
EP-0576229-A1 Low temperature process for preparing alpha-anomer enriched 2-deoxy-2, 2-difluoro-D-ribofuranosyl sulfonates ELI LILLY AND COMPANY (US) 1993-12-29 EP claimed
US-5252756-A Process for preparing beta-anomer enriched 2-deoxy-2,2-difluoro-D-ribofuranosyl-arylsulfonates ELI LILLY AND COMPANY (US) 1993-10-12 US claimed
EP-0193347-B1 13-SUBSTITUTED DERIVATIVES OF AVERMECTIN AGLYCONES MERCK & CO. INC. (US) 1990-08-29 EP claimed
EP-0193347-A2 13-Substituted derivatives of avermectin aglycones MERCK & CO. INC. (US) 1986-09-03 EP claimed